Sleep Disturbance as a Mediator of Lung Cancer Stigma on Psychological Distress and Physical Symptom Burden

Dados Bibliográficos

ID19306348
AutoresTimothy J Williamson (0000-0002-3678-0657, Angeles University Foundation, autor correspondente), Edward B Garon (0000-0001-7077-8801, Angeles University Foundation), Michael R Irwin (0000-0002-1502-8431, Angeles University Foundation), Alyssa K Choi (0000-0002-2389-8533, Angeles University Foundation), Jonathan W Goldman (0000-0002-4925-8243, Angeles University Foundation), Annette L Stanton (0000-0001-9021-2549, Angeles University Foundation)
Ano2024
Volume86
Fascículo4
Páginas334-341
Data de publicação2024-05-01
Peer ReviewedSim
Open AccessNão
TipoARTICLE
PeriódicoPsychosomatic Medicine (JOURNAL)
Identificadores do periódicoISSN: 0033-3174 • E-ISSN: 1534-7796
EditoraOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/psy.0000000000001299
PMID38436657
OpenAlexW4392368943
IdiomaEN
Citações recebidas1
Referências citadas66

OBJECTIVE: This study tested sleep disturbance as a mediator through which stigma and discrimination predict psychological distress and physical symptom burden in adults with lung cancer. METHODS: Lung cancer patients on active oncological treatment ( N = 108; 74.1% stage IV) completed questionnaires on lung cancer stigma, sleep, distress, and physical symptoms at study entry and at 6- and 12-week follow-up. Mediation analyses were conducted to investigate whether stigma and discrimination predicted distress and physical symptoms at study entry and across 12 weeks through disrupted sleep. RESULTS: Higher discrimination ( b = 5.52, 95% confidence interval [CI] = 2.10-8.94) and constrained disclosure ( b = 0.45, 95% CI = 0.05-0.85) were associated significantly with higher sleep disruption at study entry. Sleep disruption, in turn, was associated with higher distress ( b = 0.19, 95% CI = 0.09-0.29) and physical symptoms ( b = 0.28, 95% CI = 0.17-0.40) at study entry. Sleep disruption significantly mediated relationships between higher discrimination and the outcomes of distress (indirect effect = 1.04, 95% CI = 0.13-1.96) and physical symptoms (indirect effect = 1.58, 95% CI = 0.37-2.79) at study entry. Sleep disruption also mediated relationships between constrained disclosure and the outcomes of distress (indirect effect = 0.85, 95% CI = < 0.01-0.17) and physical symptoms (indirect effect = 0.13, 95% CI = 0.01-0.25). CONCLUSIONS: Lung cancer patients evidenced pronounced sleep disruption, which mediated relationships between indicators of lung cancer stigma and distress and physical symptoms at study entry. Research is needed to test additional mechanisms through which lung cancer stigma predicts these outcomes longitudinally

Anxiety · Distress · Human immunodeficiency virus (HIV) · Insomnia · Lung cancer · Mediator · Psychiatry · Psychological distress · Psychotherapist · Sleep (system call) · Sleep disorder · Social stigma · Stigma (botany) · Cancer survivorship and care · Clinical Psychology · Global Cancer Incidence and Screening · Internal Medicine · Medicine · Oncology · Psychology · Sleep and related disorders