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Adrenal Function and Alcoholism

II. Catecholamines

Bibliographic Data

ID19308181
AuthorsMOTOI OGATA, Jack H Mendelson (Harvard University, corresponding author), Nancy K Mello, Edward Majchrowicz
Year1971
Volume33
Issue2
Pages159-180
Publication date1971-03-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/00006842-197103000-00007
PMID5549660
OpenAlexW2023294842
LanguageEN
Citations received1

Urinary excretion of catecholamines and their metabolites were determined in alcoholic subjects during chronic ethanol ingestion and after alcohol withdrawal. A dose response relationship was found between magnitude of blood alcohol levels and increased excretion of epinephrine, metanephrine, norepinephrine and noremetanephrine. Maximal excretion of epinephrine occurred when subjects developed withdrawal signs and symptoms after they had stopped drinking. A significant decrease in excretion of VMA and a concomitant increase in MHPG excretion occurred when subjects were drinking. These data indicate that chronic ethanol ingestion is associated with both stimulation of adrenergic activity and alteration in pathways of catecholamine catabolism

Alcohol · Catecholamine · Dopamine · Epinephrine · Ethanol · Excretion · Ingestion · Metanephrine · Norepinephrine · Stimulation · Adipose Tissue and Metabolism · Chemistry · Eicosanoids and Hypertension Pharmacology · Endocrinology · Hormonal and reproductive studies · Internal Medicine · Medicine

  • Alcoholism scales and objective assessment methods

    William R Miller•Psychological Bulletin•1976

Unique citing works1
Citations per year0,02
Citation span1976 - 1976 (1)
Citation velocityhistorical
Highly citedNo

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