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Incident Stressful and Traumatic Life Events and Human Immunodeficiency Virus Sexual Transmission Risk Behaviors in a Longitudinal, Multisite Cohort Study

Bibliographic Data

ID19309510
AuthorsBrian W Pence (0000-0001-7321-9538, Duke University), James L Raper (0000-0002-3242-4911), Susan Reif (0000-0002-1387-7202), Nathan M Thielman (0000-0001-8152-2879), Jane Leserman, Michael J Mugavero, Michael Mugavero (0000-0001-6916-6701)
Year2010
Volume72
Issue7
Pages720-726
Publication date2010-09-01
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/psy.0b013e3181e9eef3
PMID20595416
PMCIDPMC3691861
OpenAlexW2058069321
LanguageEN
Citations received7
References cited31

Objective: To assess the association between incident stressful life events (e.g., sexual and physical assault; housing instability; and major financial, employment, and legal difficulties) and unprotected anal or vaginal sexual intercourse (unprotected sex) among people living with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (PLWHA). Methods: We assessed incident stressful events and unprotected sex over 27 months in 611 participants in an eight-site, five-state study in the Southeast United States. Using mixed-effects logistic models and separately estimating between-person and within-person associations, we assessed the association of incident stressful events with unprotected sex with all partners, HIV-positive partners, and HIV-negative/serostatus-unknown partners. Results: Incident stressful events reported at one third or more of interviews included major illness, injury or accident (non-HIV-related); major illness of a family member/close friend; death of a family member/close friend; financial stresses; and relationship stresses. In multivariable models, each additional moderately stressful event an individual experienced at a given time point above his or her norm (within-person association) was associated with a 24% to 27% increased odds of unprotected sex for each partner type. Conclusions: Risk reduction among PLWHA remains a major focus of efforts to combat the HIV epidemic. Incident stressful events are exceedingly common in the lives of PLWHA and are associated with increased unprotected sex. Efforts to either prevent the occurrence of such events (e.g., financial or relationship counseling) or address their sequelae (e.g., coping skills or other behavioral counseling) may help reduce secondary HIV transmission. aOR = adjusted odds ratio; BSI = Brief Symptoms Inventory; CHASE = Coping with HIV/AIDS in the Southeast; CI = confidence interval; MSM = men who have sex with men; OR = odds ratio; PCS = Physical Composite Score; PLWHA = people living with human immunodeficiency virus/acquired immunodeficiency syndrome; SF-36 = Medical Outcomes Study Short Form-36

Cohort · Family medicine · Human immunodeficiency virus (HIV) · Logistic regression · Odds ratio · Psychiatry · Serostatus · Viral load · Adolescent Sexual and Reproductive Health · Child Abuse and Trauma · Clinical Psychology · Demography · HIV/AIDS Research and Interventions · Internal Medicine · Medicine · Psychology

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Citations per year0.47
Citation span2011 - 2023 (13)
Highly citedNo

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