Circadian cortisol secretion and circadian adrenal responses to ACTH are maintained in dexamethasone suppressed capuchin monkeys ( Cebus apella )
Bibliographic Data
| ID | 19386685 |
|---|---|
| Authors | Claudia Torres‐Farfan (0000-0001-5573-6611, Pontificia Universidad Católica de Chile), Francisco Valenzuela (University of Chile), Francisco J Valenzuela, Renato Ebensperger (Pontificia Universidad Católica de Chile), Natalia Méndez (0000-0001-9912-8829, Pontificia Universidad Católica de Chile), Carmen Campino (0000-0002-8764-9659, Pontificia Universidad Católica de Chile), Hans Richter (0000-0002-4903-1807, Austral University of Chile), Hans G Richter, Guillermo J Valenzuela (0000-0003-1552-8812, Arrowhead Regional Medical Center), María Serón‐Ferré (0000-0002-0343-1311, University of Tarapacá, corresponding author) |
| Year | 2008 |
| Volume | 70 |
| Issue | 1 |
| Pages | 93-100 |
| Publication date | 2008-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Primatology (JOURNAL) |
| Journal identifiers | ISSN: 0275-2565 • E-ISSN: 1098-2345 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajp.20461 |
| PMID | 17620278 |
| OpenAlex | W2068659635 |
| Language | EN |
| Citations received | 1 |
| References cited | 28 |
We tested the hypothesis that the capuchin monkey adrenal ( Cebus apella ) gland has oscillatory properties that are independent of adrenocorticotropic hormone (ACTH) by exploring under ACTH suppression by dexamethasone: (i) maintenance of a circadian rhythm of plasma cortisol and (ii) clock time dependency of plasma cortisol response to exogenous ACTH. The capuchin monkey had a clear ACTH and plasma cortisol rhythm. Dexamethasone treatment resulted in low non‐rhythmic ACTH levels and decreased cortisol to 1/10 of control values; nevertheless, the circadian rhythm of plasma cortisol persisted. We found that cortisol response to exogenous ACTH was clock time‐dependent. The maximal response to ACTH occurred at the acrophase of the cortisol rhythm (0800 h). These results suggest that the capuchin monkey adrenal cortex may possess intrinsic oscillatory properties that participate in the circadian rhythm of adrenal cortisol secretion and in the circadian cortisol response to ACTH. Am. J. Primatol. 70:93–100, 2008. © 2007 Wiley‐Liss, Inc
Adrenal cortex · Adrenal gland · Adrenocorticotropic hormone · Biology · Cebidae · Circadian clock · Circadian rhythm · Dexamethasone · Glucocorticoid · Hormone · Hydrocortisone · Rhythm · Adipose Tissue and Metabolism · Circadian rhythm and melatonin · Medicine · Stress Responses and Cortisol · Endocrinology · Internal Medicine
| Citations per year | 0.11 |
|---|---|
| Citation span | 2017 - 2017 (1) |
| Highly cited | No |