Course and characteristics of depression over a 12-month period among Ghanaians living with HIV
The Everlast study
Bibliographic Data
| ID | 19438654 |
|---|---|
| Authors | Nana Kwame Ayisi‐Boateng (0000-0002-0961-4434, Kwame Nkrumah University of Science and Technology), Nana Kwame Ayisi-Boateng (Kwame Nkrumah University of Science and Technology, Kumasi, Ghana), Samuel Blay Nguah (0000-0002-2118-7711, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana), John‐Paul Omuojine (0000-0001-7320-6104, Komfo Anokye Teaching Hospital, Kumasi, Ghana), Bruce Ovbiagele (0000-0002-9958-0644, University of California, San Francisco, CA, USA), Fred Stephen Sarfo (0000-0001-7274-5093, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, corresponding author) |
| Year | 2022 |
| Volume | 34 |
| Issue | 12 |
| Pages | 1547-1554 |
| Publication date | 2022-12-02 |
| Open Access | No |
| Type | ARTICLE |
| Venue | AIDS Care (JOURNAL) |
| Journal identifiers | ISSN: 0954-0121 • E-ISSN: 1360-0451 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/09540121.2022.2029821 |
| PMID | 35084272 |
| OpenAlex | W4210670008 |
| Language | EN |
| References cited | 23 |
Individuals with HIV are predisposed to depression but there is limited data on its dynamics and correlates. We aimed to assess course and characteristics of depression among Ghanaian HIV patients over a 12-month period. We interrogated a longitudinal study dataset of patients at a tertiary hospital and assessed depression at month 0 and 12 using the Patient Health Questionnaire-9 (PHQ-9). Association between clinical, sociodemographic factors and changes in PHQ-9 scores were evaluated. Among 320 study participants, 171 (53.4%) and 55 (17.2%) had depression at month 0 and 12 respectively. Persistent depression was detected in 41 (24.0%) of the 171 patients with depression at month 0, whilst 135 (42.2%) of them never experienced depression. Patients' CD4 count was associated with depression at month 0 and 12 (p<0.05). Predictors of change in depression scores were urban dwelling [-1.98, 95%CI: -3.86 to -0.06, p=0.039], not knowing one's monthly income [2.10, 95%CI: 0.58 to 3.61, p=0.007], participant being single [-1.62 95%CI: -2.45 to -0.78, p<0.001] and being on antiretroviral therapy at recruitment [-1.5, 95%CI: -2.55 to -0.45, p<0.001]. There was a significant decrease in depression scores over a 12-month period and persistent depression is rife among this cohort of Ghanaians with HIV
Anxiety · Cohort · Cohort study · Depressive symptoms · Longitudinal study · Patient Health Questionnaire · Psychiatry · HIV-related health complications and treatments · HIV/AIDS Research and Interventions · Maternal Mental Health During Pregnancy and Postpartum · Medicine · Immunology · Internal Medicine
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| Highly cited | No |
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