The Case adherence index

The Center for Adherence Support Evaluation (CASE) Adherence Index, a simple composite measure of self-reported antiretroviral therapy (ART) adherence, was compared to a standard three-day self-reported adherence measure among participants in a longitudinal, prospective cross-site evaluation of 12 adherence programs throughout the United States. The CASE Adherence Index, consisting of three unique adherence questions developed for the cross-site study, along with a three-day adherence self-report were administered by interviews every three months over a one-year period. Data from the three cross-site adherence questions (individually and in combination) were compared to three -day self-report data and HIV RNA and CD4 outcomes in cross-sectional analyses. The CASE Adherence Index correlated strongly with the three-day self-reported adherence data (p 10 achieved a 98 cell mean increase in CD4 count over 12 months, compared to a 41 cell increase for those with scores < or =10 (p < 0.05). The CASE Adherence Index is an easy to administer instrument that provides an alternative method for assessing ART adherence in clinical settings

Antiretroviral therapy · Cross-sectional study · Family medicine · Medication adherence · Pathology · Physical therapy · Viral load · HIV Research and Treatment · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Medicine · Internal Medicine

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• Protocol of a randomized controlled trial to test the effects of client-centered Representative Payee Services on antiretroviral therapy adherence among marginalized people living with HIV

  Open Access•Abisola Olaniyan, Stephanie L Creasy et al.•BMC Public Health•2020

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• Practical and Conceptual Challenges in Measuring Antiretroviral Adherence

  Karina M Berg, Julia H Arnsten•JAIDS Journal of Acquired Immune…•2006

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• The Association of HIV-Related Stigma to HIV Medication Adherence

  Open Access•Shannon M Sweeney, Peter A Vanable•AIDS and Behavior•2016

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• Examining the Implementation of Conditional Financial Incentives Using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) Framework to Improve HIV Outcomes among Persons Living with HIV (PLWH) in Louisiana

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• The prevalence of overweight/obesity and its association with household food insecurity among women living with HIV in rural Eswatini

  Open Access•Nozipho Becker, Andile Mkhonta et al.•BMC Public Health•2022

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• Intimate partner violence and its associations among HIV-infected MSM with new drug abuse in Jinan, China

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• Risky Alcohol Consumption and Associated Health Behaviour Among HIV-Positive and HIV-Negative Patients in a UK Sexual Health and HIV Clinic

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• Cultural Adaption, Translation, Preliminary Reliability and Validity of Key Psychological and Behavioural Measures for 18 to 25 Year-Olds Living with HIV in Uganda

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• The Association of Distinct Social Determinants of Health with Added Sweetener Knowledge and Consumption in a U.S. Sample of People Living with HIV

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• Concomitant herbal medicine and Antiretroviral Therapy (ART) use among HIV patients in Western Uganda

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• Access to antiretroviral therapy during excess black-water flooding in central Thailand

  Thana Khawcharoenporn, Anucha Apisarnthanarak et al.•AIDS Care•2013

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• Proactive coping and spirituality among patients who left or remained in antiretroviral treatment in St Petersburg, Russian Federation

  Anna Pecoraro, Aureliano Pacciolla et al.•AIDS Care•2016

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• Lost-to-care and engaged-in-care HIV patients in Leningrad Oblast, Russian Federation

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• Factors influencing social self-disclosure among adolescents living with HIV in Eastern Africa

  Open Access•Christiana Nöstlinger, Sabrina Bakeera-Kitaka et al.•AIDS Care•2015

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• Effects of an intervention addressing information, motivation, and behavioral skills on HIV care adherence in a southern clinic cohort

  Deborah J Konkle-Parker, K Rivet Amico et al.•AIDS Care•2014

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• Relationship between viral load and self-report measures of medication adherence among youth with perinatal HIV infection

  Ann Usitalo, Erin Leister et al.•AIDS Care•2014

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• Depression, adherence and attrition from care in HIV-infected adults receiving antiretroviral therapy

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• Disability and health outcomes - from a cohort of people on long-term anti-retroviral therapy

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• Self-compassion and reactions to serious illness

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• Cultural adaption, translation, preliminary reliability and validity of psychological and behavioural measures for adolescents living with HIV in Botswana

  Open Access•Michael Evangeli, Ina Kaleva et al.•Journal of Health Psychology•2025

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• The Consistency of Adherence to Antiretroviral Therapy Predicts Biologic Outcomes for Human Immunodeficiency Virus–Infected Persons in Clinical Trials

  Sharon Mannheimer, Gerald Friedland et al.•Clinical Infectious Diseases•2002

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• Comparing the Areas under Two or More Correlated Receiver Operating Characteristic Curves

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• Measuring Adherence to Antiretroviral Therapy in a Diverse Population Using a Visual Analogue Scale

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• Impact of Adherence and Highly Active Antiretroviral Therapy on Survival in HIV-Infected Patients

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• Responses to a 1 month self-report on adherence to antiretroviral therapy are consistent with electronic data and virological treatment outcome

  John Walsh, John C Walsh et al.•AIDS•2002

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• Non-adherence to highly active antiretroviral therapy predicts progression to Aids

  David R Bangsberg, Sharon Perry et al.•AIDS•2001

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• Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population

  David R Bangsberg, FREDERICK HECHT et al.•AIDS•2000

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• Antiretroviral Therapy Adherence and Viral Suppression in HIV‐Infected Drug Users

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• A Comparison Study of Multiple Measures of Adherence to HIV Protease Inhibitors

  Open Access•Honghu Liu, Carol E Golin et al.•Annals of Internal Medicine•2001

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• Intermittent use of triple-combination therapy is predictive of mortality at baseline and after 1 year of follow-up

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• Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection

  Open Access•David L Paterson, Susan Swindells et al.•Annals of Internal Medicine•2000

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• The meaning and use of the area under a receiver operating characteristic (ROC) curve.

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• Self-reported adherence to antiretroviral medications among participants in HIV clinical trials

  Margaret A Chesney, Jeannette R Ickovics et al.•AIDS Care•2000

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• Quality of life in HIV-infected individuals receiving antiretroviral therapy is related to adherence

  Sharon Mannheimer, S B Mannheimer et al.•AIDS Care•2005

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• Comparing Objective Measures of Adherence to HIV Antiretroviral Therapy

  Open Access•David R Bangsberg, FREDERICK HECHT et al.•AIDS and Behavior•2001

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