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Psychosocial correlates of awareness of HIV pre-exposure prophylaxis (PrEP) among persons who inject drugs in Northeast Georgia

Bibliographic Data

ID19440629
AuthorsMohammad Rifat Haider (0000-0002-0690-8242, University of Georgia, corresponding author), Samantha Clinton (University of Georgia), Jemema Zaman (0009-0000-8400-2203, University of Georgia), MD Faisal Ahmed (0000-0001-7190-8591, University of Georgia), Fardin Ahmed, Rekha Mehra (0000-0002-9794-2971, University of California, San Francisco), Renée Mehra, Sean Arayasirikul (0000-0001-7698-6206, University of California, Irvine), Willi Mcfarland (0000-0002-4148-5660, University of California, San Francisco), Ali Mirzazadeh (0000-0002-0478-3220, University of California, San Francisco), E Jennifer Edelman (0000-0002-9375-0489, Yale University), Nathan B Hansen (0000-0001-6098-8039, University of Georgia)
Year2026
Volume38
Issue5
Pages964-977
Publication date2026-05-04
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2025.2592886
PMID41318110
OpenAlexW4416819412
LanguageEN
References cited66

Despite Georgia having one of the highest rates of new HIV diagnoses in the United States, uptake of HIV pre-exposure prophylaxis (PrEP) remains critically low. We assessed the psychosocial correlates associated with PrEP awareness among persons who inject drugs (PWID) living in Northeast Georgia. Data were collected from 173 adult (≥18 years) HIV-negative PWID. PrEP awareness was elicited by the question, "Have you ever heard of PrEP?" (Yes/No). Covariates include age, gender, sexual orientation, race/ethnicity, education, health insurance, HIV testing, syringe services program (SSP) attendance, psychological stress, resilience, risky sexual and injection behaviors, HIV information seeking, and primary drugs used. Less than half (47.4%) of participants were aware of PrEP. Most participants were interested in asking for PrEP information from providers, obtaining prescriptions, and taking PrEP. In the multivariable analysis, the odds of PrEP awareness were higher among PWID who had higher resilience (adjusted OR: 1.06, 95%CI: 1.02-1.10), ever attended an SSP (adjusted OR: 2.53, 95%CI: 1.21-5.63) and performed sexualized drug use in the last year (adjusted OR: 2.38, 95%CI: 1.01-5.63). PrEP awareness is the first step in the HIV prevention continuum, influencing initiation, use, and persistence. A resilience-based approach in SSP settings may effectively increase PrEP awareness among PWID

Harm reduction · Injection drug use · Odds · Odds ratio · Pre-exposure prophylaxis · Psychological intervention · Psychosocial · Syringe · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Sex work and related issues

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