Patient-perceived barriers to antiretroviral adherence

Associations with race

Bibliographic Data

ID19442913
AuthorsT F Ferguson (University of Alabama), Kenneth Stewart (0000-0001-9768-0417, AIDS United), K E Stewart (b Division of Preventive Medicine, Department of Medicine , UAB), Ellen Funkhouser (0000-0002-9689-6491, Alabama Department of Public Health), Jerry M Tolson (Wellcome Library), J Tolson (d Glaxo-Wellcome, Inc , USA), Andrew O Westfall (0000-0002-0468-4695, Comprehensive Blood & Cancer Center), Michael S Saag (0000-0002-8866-1043, AIDS United)
Year2002
Volume14
Issue5
Pages607-617
Publication date2002-10-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/0954012021000005434
PMID12419110
OpenAlexW1983769732
LanguageEN
Citations received18
References cited26

New antiretroviral (ARV) regimens require strict adherence if optimal suppression of HIV is to be maintained. This study is a theory-based examination of racial differences in patient-perceived barriers and reported ARV adherence. Participants (N=149) completed the Patient Medication Adherence Questionnaire (PMAQ), measuring adherence and perceived barriers to adherence. Adherence was defined as a self-report of 100% adherence in the past four weeks. Odds ratios were calculated to determine the relation of reported barriers to adherence for race and gender groups, and for the sample overall. For every ten-point increase in barrier score, there was an 86% increased risk of being non-adherent (OR=1.86; 95% CI: 1.19, 2.91). Adherence was not different between racial and gender groups, nor was total barrier score. However, individual barriers were differentially endorsed across groups. Rather than relying on demographic predictors, which may be only an indirect marker of adherence, evaluations of adherence should examine the psychological and social barriers to positive adherence outcomes in individual patients. Our findings support the use of theory-based behavioural interventions that address perceived barriers to adherence and other health promotion activities

Family medicine · Medication adherence · Psychiatry · Psychological intervention · Adolescent Sexual and Reproductive Health · Clinical Psychology · HIV/AIDS Research and Interventions · LGBTQ Health, Identity, and Policy · Medicine · Internal Medicine

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