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Understanding cultural values, norms and beliefs that may impact participation in genome‐editing related research

Perspectives of local communities in Botswana

Bibliographic Data

ID19516500
AuthorsSetlhomo Koloi‐Keaikitse (0000-0002-3402-2836, University of Botswana, corresponding author), Mary Kasule (0000-0002-9054-1518, University of Botswana), Irene Kwape (0000-0003-0282-8007, University of Botswana), Dudu Jankie (0009-0005-8422-6879, University of Botswana), Dimpho Ralefala (0000-0001-9074-0405, University of Botswana), Dolly Mogomotsi Ntseane (0000-0001-5698-1934, University of Botswana), Gaonyadiwe George Mokone (0000-0002-9641-064X, University of Botswana)
Year2025
Volume25
Issue1
Pages24-34
Publication date2025-03-01
Open AccessYes
TypeARTICLE
VenueDeveloping World Bioethics (JOURNAL)
Journal identifiersISSN: 1471-8731 • E-ISSN: 1471-8847
PublisherWiley (PUBLISHER • GB)
DOI10.1111/dewb.12440
PMID38205946
OpenAlexW4390744291
LanguageEN
Citations received2

Gene‐editing research is a complex science and foreign in most communities including Botswana. Adopting a qualitative deliberative framework with 109 participants from 7 selected ethnic communities in Botswana, we explored the perceptions of local communities on cultural values, norms, and beliefs that may motivate or deter likely participation in the use of gene‐editing related research. What emerged as the ethnic community's motivators for research participation include the potential for gene‐editing technologies to promote access to individualized medications, and the possibility of protecting family members from genetic related diseases. Deterrents for research participation include cultural values such as implications of lineage for chieftainship, trust, fear or anxiety, uncertainty, and sensitivity on the use of gene‐editing. Findings of our study have implications for continuous engagement with local communities to explore potential ways of addressing cultural sensitivities that can further deter their participation in future gene‐editing related research

Community engagement · Ethnic group · Ethnography · Perception · Political science · Public relations · Qualitative research · Social science · Sociology · Anthropology · CRISPR and Genetic Engineering · Innovation and Socioeconomic Development · Psychology · Social Psychology

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Citations per year2
Citation span2025 - 2026 (2)
Highly citedNo

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Open DOIOpen Access
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