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The ventro-medial prefrontal cortex

A major link between the autonomic nervous system, regulation of emotion, and stress reactivity

Bibliographic Data

ID19536734
AuthorsAlexander Hänsel (University Hospital of Bern, corresponding author), Roland Von Känel (0000-0002-8929-5129, University Hospital of Bern)
Year2008
Volume2
Issue1
Pages21-21
Publication date2008-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueBioPsychoSocial Medicine (JOURNAL)
Journal identifiersISSN: 1751-0759 • E-ISSN: 1751-0759
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1186/1751-0759-2-21
PMID18986513
PMCIDPMC2590602
OpenAlexW2111637379
LanguageEN
Citations received3
References cited37

Recent progress in neuroscience revealed diverse regions of the CNS which moderate autonomic and affective responses. The ventro-medial prefrontal cortex (vmPFC) plays a key role in these regulations. There is evidence that vmPFC activity is associated with cardiovascular changes during a motor task that are mediated by parasympathetic activity. Moreover, vmPFC activity makes important contributions to regulations of affective and stressful situations. This review selectively summarizes literature in which vmPFC activation was studied in healthy subjects as well as in patients with affective disorders. The reviewed literature suggests that vmPFC activity plays a pivotal role in biopsychosocial processes of disease. Activity in the vmPFC might link affective disorders, stressful environmental conditions, and immune function

Autonomic nervous system · Biopsychosocial model · Cognition · Prefrontal cortex · Psychotherapist · Ventromedial prefrontal cortex · Heart Rate Variability and Autonomic Control · Medicine · Neuroscience · Psychology · Stress Responses and Cortisol · Tryptophan and brain disorders

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Unique citing works3
Citations per year0,2
Citation span2011 - 2026 (16)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 3

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