L-carnosine as an enhancer to computerized cognitive behaviour therapy in Japanese workers, an unjustified claim
Bibliographic Data
| ID | 19536748 |
|---|---|
| Authors | Geneviève Sauvé (0000-0001-8140-2578, Université du Québec à Montréal), Marie-France Bastien (Université du Québec à Montréal), Casandra Roy-Gelencser (Université du Québec à Montréal), Ghassan El-Baalbaki (0000-0002-7123-5769, Université du Québec à Montréal, corresponding author) |
| Year | 2018 |
| Volume | 12 |
| Issue | 1 |
| Pages | 11-11 |
| Publication date | 2018-12-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | BioPsychoSocial Medicine (JOURNAL) |
| Journal identifiers | ISSN: 1751-0759 • E-ISSN: 1751-0759 |
| Publisher | Springer Science and Business Media LLC (PUBLISHER) |
| DOI | 10.1186/s13030-018-0130-3 |
| PMID | 30202430 |
| OpenAlex | W2889060056 |
| Language | EN |
| Citations received | 1 |
| References cited | 11 |
This letter comments on the conclusion drawn by Shirotsuki et al. (2017) in their article entitled “The effect for Japanese workers of a self-help computerized cognitive behaviour therapy program with a supplement soft drink”, recently published in BioPsychoSocial Medicine . The authors concluded that their drink, containing L-carnosine, enhances the effects of a computerized cognitive-behavioural therapy (CCBT) on the psychological well-being of healthy Japanese workers. Yet, we argue that their conclusion is unfounded given their results and the methodological shortcomings of their study. Briefly, while the authors reported improvement on the tension-anxiety subscale of the Profile of Mood States (POMS) in the CCBT only group, they also observed a lack of improvement on this subscale in the CCBT+L-carnosine group suggesting that the drink washes out this beneficial effect of CCBT. Methodological issues include the uncontrolled levels of L-carnosine metabolized by participants jeopardize the study’s internal validity. Also, the clinical meaningfulness of the findings seems dubious as post-treatment scores remained within the range of the general Japanese population. Consequently, we argue that Shirotsuki et al.’s study should be re-conducted before drawing any valid conclusion
Anxiety · Biopsychosocial model · Carnosine · Cognition · Cognitive behaviour therapy · Mood · Psychiatry · Psychotherapist · Biochemical effects in animals · Clinical Psychology · Heart Rate Variability and Autonomic Control · Medicine · Psychology · Stress Responses and Cortisol · Internal Medicine
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| Unique citing works | 1 |
|---|---|
| Citations per year | 0,11 |
| Citation span | 2017 - 2017 (1) |
| Citation velocity | historical |
| Highly cited | No |