Association between physical multimorbidity and common mental health disorders in rural and urban Malawian settings
Preliminary findings from Healthy Lives Malawi long-term conditions survey
Bibliographic Data
| ID | 19590981 |
|---|---|
| Authors | Owen Nkoka (0000-0001-6984-2247, Malawi Epidemiology and Intervention Research Unit, corresponding author), Shekinah Munthali-Mkandawire (0000-0003-2615-1790, Malawi Epidemiology and Intervention Research Unit, corresponding author), Kondwani Mwandira (0000-0001-8362-7156, Malawi Epidemiology and Intervention Research Unit, corresponding author), Providence Nindi (Malawi Epidemiology and Intervention Research Unit, corresponding author), Albert Dube (0000-0002-6392-0475, Malawi Epidemiology and Intervention Research Unit, corresponding author), Innocent Nyanjagha (0009-0007-5132-125X, Malawi Epidemiology and Intervention Research Unit, corresponding author), Angella Mainjeni (Malawi Epidemiology and Intervention Research Unit, corresponding author), Jullita Malava (Malawi Epidemiology and Intervention Research Unit, corresponding author), Abena S Amoah (0000-0003-2270-1871, Leiden University, corresponding author), Estelle Mclean (0000-0001-6079-0663, London School of Hygiene & Tropical Medicine, corresponding author), R Stewart (0000-0002-4435-6397, Malawi Epidemiology and Intervention Research Unit, corresponding author), Robert C Stewart (0000-0002-0413-1388), Amelia C Crampin (0000-0002-1513-4330, London School of Hygiene & Tropical Medicine, corresponding author), Alison J Price (0000-0002-3891-3337, London School of Hygiene & Tropical Medicine, corresponding author) |
| Editors | John M Francis (0000-0003-1902-2683) |
| Year | 2024 |
| Volume | 4 |
| Issue | 4 |
| Pages | e0002955 |
| Publication date | 2024-04-04 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | PLOS Global Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2767-3375 • E-ISSN: 2767-3375 |
| Publisher | Public Library of Science (PLoS) (PUBLISHER) |
| DOI | 10.1371/journal.pgph.0002955 |
| PMID | 38574079 |
| OpenAlex | W4393929251 |
| Language | EN |
| Citations received | 1 |
| References cited | 69 |
In low-income Africa, the epidemiology of physical multimorbidity and associated mental health conditions is not well described. We investigated the multimorbidity burden, disease combinations, and relationship between physical multimorbidity and common mental health disorders in rural and urban Malawi using early data from 9,849 adults recruited to an on-going large cross-sectional study on long-term conditions, initiated in 2021. Multimorbidity was defined as having two or more measured (diabetes, hypertension) or self-reported (diabetes, hypertension, disability, chronic pain, HIV, asthma, stroke, heart disease, and epilepsy) conditions. Depression and anxiety symptoms were measured using the 9-item Patient Health Questionnaire (PHQ-9) and the 7-item General Anxiety Disorder scale (GAD-7) and defined by the total score (range 0–27 and 0–21, respectively). We determined age-standardized multimorbidity prevalence and condition combinations. Additionally, we used multiple linear regression models to examine the association between physical multimorbidity and depression and anxiety symptom scores. Of participants, 81% were rural dwelling, 56% were female, and the median age was 30 years (Inter Quartile Range 21–43). The age-standardized urban and rural prevalence of multimorbidity was 14.1% (95% CI, 12.5–15.8%) and 12.2% (95% CI, 11.6–12.9%), respectively. In adults with two conditions, hypertension, and disability co-occurred most frequently (18%), and in those with three conditions, hypertension, disability, and chronic pain were the most common combination (23%). Compared to adults without physical conditions, having one ( B -Coefficient ( B ) 0.79; 95% C1 0.63–0.94%), two- ( B 1.36; 95% CI 1.14–1.58%), and three- or more- physical conditions ( B 2.23; 95% CI 1.86–2.59%) were associated with increasing depression score, p -trend
Anxiety · Asthma · Comorbidity · Confidence interval · Cross-sectional study · Diabetes mellitus · Mental health · Multimorbidity · Physical therapy · Psychiatry · Quartile · Chronic Disease Management Strategies · Health disparities and outcomes · Healthcare Systems and Reforms · Medicine · Epidemiology · Internal Medicine
A call to action to address rural mental health disparities
A classification of chronic pain for ICD-11
An overview of systematic reviews on the public health consequences of social isolation and loneliness
Defining Comorbidity
The role of inflammation in depression
Multimorbidity and depression
A diagnostic meta-analysis of the Patient Health Questionnaire-9 (PHQ-9) algorithm scoring method as a screen for depression
The association between social relationships and depression
The Critical Relationship Between Anxiety and Depression
Global and regional prevalence of multimorbidity in the adult population in community settings
State of the Art Review
Mental Health Service Provision in Low- and Middle-Income Countries
A Brief Measure for Assessing Generalized Anxiety Disorder
The PHQ-9
Patterns of multimorbidity in India
Impact of the Acceptance of Disability on Self-Esteem among Adults with Disabilities
Multimorbidity Patterns in the General Population
Measuring disability and monitoring the UN Convention on the Rights of Persons with Disabilities
Access to health care for people with disabilities in rural Malawi
Burden and changes in HIV/Aids morbidity and mortality in Southern Africa Development Community Countries, 1990–2017
Physical Multimorbidity and Social Participation in Adult Aged 65 Years and Older From Six Low- and Middle-Income Countries
Experiences of multimorbidity in urban and rural Malawi
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,5 |
| Citation span | 2024 - 2024 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |