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Determinants of Covid-19 vaccine hesitancy among healthcare personnel in a secondary-level health facility in Ghana

Bibliographic Data

ID19591493
AuthorsGloria Addobea Kumi (University of Health and Allied Sciences, corresponding author), Mawuli Gohoho (0009-0001-4357-3509, Ghana Health Service, corresponding author), Fortress Yayra Aku (0000-0002-9004-348X, University of Health and Allied Sciences, corresponding author)
EditorsAbram Luther Wagner (0000-0003-4691-7802)
Year2025
Volume5
Issue9
Pagese0004980
Publication date2025-09-18
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0004980
PMID40966242
OpenAlexW4414344282
LanguageEN
References cited75

Vaccine hesitancy has been a long-standing concern globally and emerged during the COVID-19 pandemic among healthcare personnel. This study assessed the prevalence and determinants of vaccine hesitancy among healthcare personnel at the Volta Regional Hospital in Ghana. A cross-sectional study was conducted among 419 randomly selected healthcare personnel to collect sociodemographic, individual-level, community-level, and health system-level data, including vaccine uptake. Multivariable logistic regression analysis was performed to assess determinants of COVID-19 vaccine hesitancy at a 95% confidence level. COVID-19 vaccine hesitancy was found in 105 (25.1%) of respondents. Increased odds of vaccine hesitancy were associated with having 6–10 years of work experience (AOR = 3.43 95% CI = 1.44–8.18), being a midwife (AOR = 2.72 95% CI = 1.15–6.46), belief that vaccination does not guarantee protection against re-infection (AOR = 5.21 95% CI = 1.79–15.22), fear of long-term effects of COVID-19 (AOR = 2.14 95% CI = 1.18–3.86), perception of increased adverse effects among vaccinated individuals (AOR = 2.79 95% CI = 1.37–5.66), and community perception of long-term health effects of vaccination (AOR = 2.69 95% CI = 1.26–5.78). Awareness that health facilities were available to manage adverse effects reduced the odds of hesitancy (AOR = 0.23 95% CI = 0.12–0.43). Our study found that one in four healthcare personnel in the Volta Regional Hospital reported hesitancy toward receiving the COVID-19 vaccine. Targeted risk communication and confidence-building strategies tailored to midwives and healthcare workers with longer years of service, including interventions aimed at improving perceptions of vaccine efficacy and safety, may enhance COVID-19 vaccine uptake

Health care · Health facility · Logistic regression · Odds · Odds ratio · Pandemic · Psychological intervention · Vaccination · COVID-19 epidemiological studies · SARS-CoV-2 and COVID-19 Research · Vaccine Coverage and Hesitancy

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