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Cholera in Kenya

A scoping review of current research, evidence gaps and future directions

Bibliographic Data

ID19594119
AuthorsKevin Wamae (0000-0001-7721-5534, Kenya Medical Research Institute, corresponding author), John Magudha (0009-0006-1766-0402, Kenya Medical Research Institute), Agnetor Kakungu (0009-0003-9263-3226, Kenya Medical Research Institute), Steve Aricha (Ministry of Health), Daniel Langat (Ministry of Health), Samson Kinyanjui (0000-0002-3910-0450, Angkor Hospital for Children), Jolynne Mokaya (0000-0001-8398-0689, Wellcome Sanger Institute), Nicole Renick Thomson (0000-0002-4432-8505, Wellcome Sanger Institute), Nicholas R Thomson (Wellcome Sanger Institute), Charles Agoti (0000-0002-2160-567X, Kenya Medical Research Institute), George Githinji (0000-0001-9640-7371, Kenya Medical Research Institute)
EditorsTinsae Alemayehu (0000-0003-0699-8433)
Year2026
Volume6
Issue3
Pagese0006011
Publication date2026-03-31
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0006011
PMID41915726
OpenAlexW7147673067
LanguageEN
References cited85

Cholera remains a major public health challenge in Kenya, driven by environmental pollution, poor water, sanitation, and hygiene (WASH) facilities, weak monitoring systems, and climate effects. While there have been improvements in studying the disease, testing, monitoring, and environmental checks, the spread continues, especially in informal settlements, rural areas, and refugee camps. This review looked at 106 peer-reviewed studies published between 1979 and 2024. It aimed to describe the scope, progress, and gaps in cholera research in Kenya. Five databases, including Google Scholar, Web of Science, PubMed, Embase, and Scopus, were searched using the terms “cholera” and “Kenya.” Titles and abstracts were reviewed using Rayyan, and data were collected using a standard form that noted study goals, methods, findings, limitations, and geographic coverage. The evidence was analysed thematically, and trends were tracked over time. Among 845 records found, 106 met the criteria for inclusion. The literature consistently connects cholera outbreaks in Kenya to climate events like flooding, drought, and El Niño, with greater vulnerability seen in informal settlements and refugee areas. Surveillance systems are still disconnected, often leading to delays in reporting and limited information at sub-county levels. Assessments of the health system reveal ongoing issues, including a shortage of laboratory resources and necessary tests. Despite innovations such as rapid diagnostic tests, whole-genome sequencing, and spatial modelling that have enhanced outbreak detection and understanding of transmission, their regular use is hindered by cost, infrastructure, and workforce issues. Social and behavioural factors, such as low-risk perception and gaps between knowledge and practice, also contribute to continued transmission. In summary, controlling cholera in Kenya needs a coordinated, multi-faceted approach. This should focus on strengthening surveillance, improving WASH facilities, increasing laboratory and molecular capabilities, expanding vaccine access, and fostering community-led efforts to turn scientific progress into effective public health measures

Cholera · Geographic information system · Human settlement · Outbreak · Pandemic · Public health · Refugee · Social vulnerability · Vulnerability (computing) · Child Nutrition and Water Access · Vibrio bacteria research studies · Viral Infections and Outbreaks Research

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