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Prevalence of metabolic syndrome and its association with cardiovascular disease risk and common risk factors amongst healthcare workers in Pakistan

Bibliographic Data

ID19594374
AuthorsUnab I Khan (0000-0002-7002-1726, Aga Khan University Hospital, corresponding author), Sonya F Khan (Ziauddin University, corresponding author), Asra Qureshi (0000-0002-6919-6238, Aga Khan University Hospital, corresponding author)
EditorsBadal Kumar Datta (0000-0002-2559-850X), Biplab Datta (0000-0002-9498-8640)
Year2025
Volume5
Issue3
Pagese0004135
Publication date2025-03-03
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0004135
PMID40029896
OpenAlexW4408100938
LanguageEN
References cited22

Metabolic syndrome (MetS) significantly increases the risk of cardiovascular disease (CVD). Healthcare workers (HCWs) are at a higher risk of CVD. However, little is known about the association between MetS and CVD risk in healthcare workers in Pakistan. We aimed to assess the prevalence of MetS and its components and examined the association between MetS and 10-year CVD-risk using Framingham Risk Score (FRS) and common CVD risk factors amongst HCWs working in a private healthcare system in Pakistan. This cross-sectional study uses baseline data from an existing CVD risk screening program for employees at a private healthcare system in Pakistan. MetS was diagnosed using the American Heart Association cut-offs for Asian population. Healthcare workers were divided into MetS positive and negative groups; demographics, MetS components and CVD risk were compared between these groups. Logistic regression was used to examine the association of MetS with 10-year CVD-risk and its risk factors. In 1,807 healthcare workers, 677 (37%) had MetS and 48 (2.7%) had a high 10-year CVD-risk. Of the MetS components, low High-density Lipoprotein (HDL) 1,467 (81%) and elevated waist circumference (WC) 1,049 (58%) were the most prevalent. Compared to MetS negative group, MetS positive group had a higher proportion of high-risk CVD (0.7% vs. 5.9%; p

Disease · Environmental health · Health care · Metabolic syndrome · Obesity · Political science · Chronic Disease Management Strategies · Diabetes, Cardiovascular Risks, and Lipoproteins · Health Promotion and Cardiovascular Prevention · Medicine · Psychology · Internal Medicine

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