Antimycobacterial evaluation of fifteen medicinal plants in South Africa
Bibliographic Data
| ID | 20346374 |
|---|---|
| Authors | T Mmushi, T J Mmushi (University of Limpopo), Peter Masoko (0000-0002-8076-083X, University of Limpopo, corresponding author), L Mde (University of Limpopo), M P Mokgotho (0000-0003-0779-562X, University of Limpopo), M Mokgotho, Leseilane Mampuru (0000-0001-5544-8863, University of Limpopo), Robert Howard (0000-0002-3071-2338, University of Limpopo) |
| Year | 2010 |
| Volume | 7 |
| Issue | 1 |
| Pages | 34-9 |
| Publication date | 2010-07-30 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | African Journal of Traditional Complementary and Alternative Medicines (JOURNAL) |
| Journal identifiers | ISSN: 0189-6016 • E-ISSN: 2505-0044 |
| Publisher | African Journals Online (AJOL) (PUBLISHER) |
| DOI | 10.4314/ajtcam.v7i1.57230 |
| PMID | 21304610 |
| OpenAlex | W2104578833 |
| Language | EN |
| Citations received | 4 |
| References cited | 4 |
Fifteen plant species were collected from the Nelspruit Botanical Garden based on a list of plants provided by Phytomedicine Programme at the University of Pretoria and their ethnopharmacological information. Hexane, dichloromethane (DCM), acetone and methanolic extracts were screened for antimycobacterial activity against Mycobacterium smegmatis. The acetone extract of Milletia stulhimannii was the most active, showing activity against Mycobacterium smegmatis with minimum inhibitory concentration (MIC) value of 0.13 mg/ml. Acetone extracts for all plants had lower MIC values ranging between 0.11-1.25 mg/ml against M. smegmatis. Milletia stulhimannii, Albizia gummifera, Xanthocercis zambesiaca and Barringtonia racemosa have shown great potential as anti-tuberculosis agents. They were active against M. smegmatis with average MIC values of acetone extracts of 0.13 mg/ml
Acetone · Antimicrobial · Antimycobacterial · Biology · Dichloromethane · Medicinal plants · Minimum inhibitory concentration · Mycobacterium smegmatis · Mycobacterium tuberculosis · Phytomedicine · Traditional medicine · Tuberculosis · Chemistry · Ethnobotanical and Medicinal Plants Studies · Medicine · Mycobacterium research and diagnosis · Phytochemistry and Bioactive Compounds · Biochemistry · Microbiology
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| Citations per year | 0.44 |
|---|---|
| Citation span | 2017 - 2025 (9) |
| Highly cited | No |