Evaluation of anti-bacterial and wound healing activity of the fruits of Amorpha fruticosa l
Bibliographic Data
| ID | 20346424 |
|---|---|
| Authors | Xiaoyan Qu (0000-0001-5407-8493, Dalian Medical University), Yuxuan Diao (Dalian Medical University), Z Zhang (0000-0002-8905-3357, Dalian Medical University), Shaopeng Wang (0000-0002-9430-8879, Dalian Medical University), Yuan Jia (0000-0002-7928-3917, Dalian Medical University) |
| Year | 2013 |
| Volume | 10 |
| Issue | 3 |
| Pages | 458-68 |
| Publication date | 2013-05-07 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | African Journal of Traditional Complementary and Alternative Medicines (JOURNAL) |
| Journal identifiers | ISSN: 0189-6016 • E-ISSN: 2505-0044 |
| Publisher | African Journals Online (AJOL) (PUBLISHER) |
| DOI | 10.4314/ajtcam.v10i3.12 |
| PMID | 24146475 |
| OpenAlex | W1972394700 |
| Language | EN |
| Citations received | 1 |
| References cited | 2 |
As the traditional Chinese medicine, the fresh fruits of Amorpha fruticosa L. were applied for the treatment of carbuncle, eczema and burn (Das et al., 2007). However, little is known about the functional roles of the fruits of Amorpha fruticosa L. during wound healing progress. In the present study, we evaluated both antimicrobial potential against a wide range of microorganisms and wound healing activity of the seven compounds isolated from the fruits of Amorpha fruticosa L in vitro and in vivo. Our results showed that compounds I (6a,12a-dehydroamorphin), V (dehydrosermundone) and VI (tephrosin) isolated from the fruits of Amorpha fruticosa L. performed dominant antimicrobial potential against microorganisms. Moreover, these compounds significantly enhanced fibroblasts proliferation and migration, leading to promotion of wound healing. Thus, it could be possible for the therapeutic utilization of Amorpha fruticosa L. for wound healing in the future
Antimicrobial · Biology · Traditional medicine · Wound healing · Chemistry · Medicine · Polysaccharides and Plant Cell Walls · Silk-based biomaterials and applications · Wound Healing and Treatments · Immunology · Microbiology
| Unique citing works | 1 |
|---|---|
| Citations per year | 0.08 |
| Citation span | 2013 - 2013 (1) |
| Citation velocity | historical |
| Highly cited | No |