Histological changes in male accessory reproductive organs in rats exposed to cigarette smoke and the protective effect of honey supplementation

Bibliographic Data

ID20346973
AuthorsMahaneem Mohamed (0000-0001-9333-1957, Universiti Sains Malaysia), Siti Amrah Sulaiman (0000-0002-6439-5449), SA Sulaiman, Hasnan Jaafar (0000-0002-6884-2920, Universiti Sains Malaysia)
Year2012
Volume9
Issue3
Pages329-35
Publication date2012-09-20
Open AccessYes
TypeARTICLE
VenueAfrican Journal of Traditional Complementary and Alternative Medicines (JOURNAL)
Journal identifiersISSN: 0189-6016 • E-ISSN: 2505-0044
PublisherAfrican Journals Online (AJOL) (PUBLISHER)
DOI10.4314/ajtcam.v9i3.5
PMID23983363
OpenAlexW1992322863
LanguageEN
Citations received1
References cited3

The effect of cigarette smoke (CS) on histology of male accessory reproductive organs and the possible protective effect of honey supplementation in rats were investigated in this study. Rats received distilled water, honey, CS exposure or honey plus CS exposure. Honey (1.2 g/kg body weight/day) was administered by gavage and CS exposure (3 times per day) was done in a chamber for 13 weeks. CS exposure significantly increased relative weight of epididymis and ventral prostate. There were also significantly increased number of clear cells and epithelial height of cauda epididymis as well as severe interstitial oedema and decreased epithelial height of prostate gland. However, with the supplementation of honey, these histological changes were significantly reversed suggesting the protective effect of honey against the toxic effect of CS on male accessory reproductive organs in rats

Andrology · Biology · Cigarette smoke · Smoke · Bee Products Chemical Analysis · Chemistry · Insect and Pesticide Research · Medicine · Phytochemicals and Antioxidant Activities · Physiology · Toxicology