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Unveiling Disparities

Analyzing Hispanic Inclusion in Liver Cancer Research Databases in the United States

Bibliographic Data

ID2073492
AuthorsGabriela Arroyo Figueroa (0000-0002-4187-4367, National Cancer Institute), Tim F Greten (0000-0002-0806-2535, National Cancer Institute), Christopher Milk Bonilla (0000-0002-5558-2744, National Cancer Institute, corresponding author)
Year2024
Volume12
Issue6
Pages3793-3804
Publication date2024-09-23
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Racial and Ethnic Health Disparities (JOURNAL)
Journal identifiersISSN: 2196-8837 • E-ISSN: 2197-3792
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s40615-024-02178-8
PMID39312090
OpenAlexW4402754804
LanguageEN
References cited66

Primary liver cancer, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma was the sixth leading cause of cancer death in the United States in 2023. Hispanic people constitute approximately 19% of the nation's total population according to the US Census. Hispanic patients have the highest relative incidence rates of liver cancer compared to non-Hispanic Whites and non-Hispanic Blacks, a disparity frequently overlooked in cancer research. In this study, our primary objective was to analyze the potential underrepresentation of Hispanic individuals in liver cancer research databases. We identified databases that had liver cancer-specific studies and be population-based in the United States. Our search yielded 7 cancer genomic databases, which were analyzed according to incidence percentages across ethnicity and race categories. Our study included 3104 patients; ethnic data was not reported for 13.1% (n = 406) of the patients. Samples were predominantly from individuals who identified as Not Hispanic (81.0%), Hispanic individuals represented 5.9%. Race was reported as follows: non-Hispanic Whites (61.0%), Asians (22.0%), non-Hispanic Blacks (5.4%), Other (3.1%), Native American/American Indian/Alaska Native (0.4%), Pacific Islander/Native Hawaiian (0.2%) and not reported (7.9%). These findings collectively underscore significant disparities in the representation of ethnic and racial groups, particularly Hispanics. Given the present racial and ethnic demographics of the US population and the projected surge in the Hispanic population in forthcoming years, it becomes imperative to address health disparities that may worsen without efforts to enhance proper inclusion in cancer research

Cancer · Cancer prevention · Census · Environmental health · Ethnic group · Health equity · Incidence (geometry · Liver cancer · Pacific islanders · Pathology · Population · Public health · Cancer Genomics and Diagnostics · Cholangiocarcinoma and Gallbladder Cancer Studies · Demography · Global Cancer Incidence and Screening · Medicine · Epidemiology · Gerontology · Internal Medicine

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