Isobavachin, a main bioavailable compound in Psoralea corylifolia, alleviates lipopolysaccharide-induced inflammatory responses in macrophages and zebrafish by suppressing the Mapk and NF-κB signaling pathways
Bibliographic Data
| ID | 21095200 |
|---|---|
| Authors | You Chul Chung (0000-0001-5411-7130, Korea Institute of Oriental Medicine), Su Jeong Song (0000-0003-2110-1874, University of Kansas), Ami Lee (0009-0002-7646-375X, Korea Institute of Oriental Medicine), Chan Ho Jang (0000-0002-0068-0152, Korea Institute of Oriental Medicine), Chan-Sik Kim (0000-0001-7610-9887, Korea Institute of Oriental Medicine), Youn-Hwan Hwang, Youn‐Hwan Hwang (0000-0002-4959-2436, Korea Institute of Oriental Medicine, corresponding author) |
| Year | 2024 |
| Volume | 321 |
| Pages | 117501 |
| Publication date | 2024-03-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2023.117501 |
| PMID | 38012970 |
| OpenAlex | W4389003595 |
| Language | EN |
| Citations received | 1 |
| References cited | 22 |
Collectively, bioavailable IBC inhibited on the inflammatory responses by LPS via MAPK and NF-κB signaling pathways in vitro and in vivo, suggesting that it may be a potential modulatory agent against inflammatory disorders
Biology · In vivo · Inflammation · Lipopolysaccharide · MAPK/ERK pathway · NF-κB · NFKB1 · Proinflammatory cytokine · Psoralea corylifolia · Signal transduction · Transcription factor · Zebrafish · Bioactive natural compounds · Chemistry · Immune Response and Inflammation · Medicine · Neuroinflammation and Neurodegeneration Mechanisms · Biochemistry · Cell Biology · Immunology · Pharmacology
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2025 - 2025 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |