Annual Research Review
Towards a deeper understanding of nature and nurture: combining family‐based quasi‐experimental methods with genomic data
Bibliographic Data
| ID | 21344155 |
|---|---|
| Authors | Tom A Mcadams (0000-0002-6825-3499, Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience King's College London London UK, corresponding author), Rosa Cheesman (0000-0002-6543-0402, Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience King's College London London UK), Yasmin I Ahmadzadeh (0000-0003-1333-1661, Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience King's College London London UK) |
| Year | 2023 |
| Volume | 64 |
| Issue | 4 |
| Pages | 693-707 |
| Publication date | 2023-04-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Child Psychology and Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 0021-9630 • E-ISSN: 1469-7610 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1111/jcpp.13720 |
| PMID | 36379220 |
| OpenAlex | W4309092814 |
| Language | EN |
| Citations received | 6 |
| References cited | 95 |
Distinguishing between the effects of nature and nurture constitutes a major research goal for those interested in understanding human development. It is known, for example, that many parent traits predict mental health outcomes in children, but the causal processes underlying such associations are often unclear. Family‐based quasi‐experimental designs such as sibling comparison, adoption and extended family studies have been used for decades to distinguish the genetic transmission of risk from the environmental effects family members potentially have on one another. Recently, these designs have been combined with genomic data, and this combination is fuelling a range of exciting methodological advances. In this review we explore these advances – highlighting the ways in which they have been applied to date and considering what they are likely to teach us in the coming years about the aetiology and intergenerational transmission of psychopathology
Biology · Data science · Developmental psychology · Family studies · Nature versus nurture · Psychopathology · Sibling · Birth, Development, and Health · Clinical Psychology · Cognitive Abilities and Testing · Computer Science · Early Childhood Education and Development · Genetics · Psychology
Something old, something new – can adding genomic data to family studies advance our understanding of the impact of nature and nurture on mental health? Commentary on McAdams et al. (2023)
Research Review
Direct and indirect genetic effects on early neurodevelopmental traits
The 20-year documentary of genetic nurturing
How Can Genetically Informative Research Contribute to Life Course Research
Cross‐Tissue Specificity of Pediatric DNA Methylation Associated With Cumulative Family Stress
Sibling Comparison Designs
The nature of nurture
Analytic approaches to twin data using structural equation models
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Parental criticism and adolescent internalising symptoms
Mechanisms linking parental educational attainment with child ADHD, depression, and academic problems
Maternal Perinatal and Concurrent Anxiety and Mental Health Problems in Early Childhood
Using DNA From Mothers and Children to Study Parental Investment in Children’s Educational Attainment
Accounting for genetic and environmental confounds in associations between parent and child characteristics
Critical Need for Family-Based, Quasi-Experimental Designs in Integrating Genetic and Social Science Research
Siblings reared apart
Testing different types of genotype-environment correlation
Genetics and analysis of quantitative traits
Social and Genetic Pathways in Multigenerational Transmission of Educational Attainment
Genotype-environment interaction and correlation in the analysis of human behavior
| Citations per year | 2 |
|---|---|
| Citation span | 2023 - 2025 (3) |
| Highly cited | No |