Towards equitable genomics governance in Africa
Guiding principles from theories of global health governance and the African moral theory of Ubuntu
Bibliographic Data
| ID | 21504385 |
|---|---|
| Authors | Nchangwi Syntia Munung (0000-0003-1498-3602, Department of Medicine University of Cape Town Cape Town South Africa, corresponding author), Jantina De Vries (0000-0001-7192-2633, Department of Medicine University of Cape Town Cape Town South Africa), Boriana Pratt (0000-0002-4934-3560, Centre for Health Equity, School of Population and Global Health University of Melbourne Melbourne Victoria Australia) |
| Year | 2022 |
| Volume | 36 |
| Issue | 4 |
| Pages | 411-422 |
| Publication date | 2022-05-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Bioethics (JOURNAL) |
| Journal identifiers | ISSN: 0269-9702 • E-ISSN: 1467-8519 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1111/bioe.12995 |
| PMID | 35041227 |
| OpenAlex | W4206423235 |
| Language | EN |
| Citations received | 4 |
| References cited | 11 |
The post‐genomics era promises a revolution characterized by precision medicine and the integration of genomics into almost every area of biomedical research. At the same time, there are concerns that if care is not taken, the genomics revolution may widen global inequities in science and health. In Africa, these concerns are primarily linked to the underrepresentation of African populations in genomics research, limited genomics research capacity in Africa and associated macro‐level justice issues such as benefit sharing, inequitable international research collaborations, and the contribution of genomics to the health and research priorities of Africa. Addressing these concerns requires an in‐depth reflection on how the ideals of global justice and equity may be advanced in genomics research. To contribute to the limited but growing scholarship on global genomics equity, especially in the African context, we performed a conceptual analysis of three accounts of justice and governance namely, Ubuntu , shared health governance and global governance of health, with the aim of identifying principles that could inform genomics governance in Africa. We used a convergence approach in the conceptual analysis, resulting in the identification of nine principles namely: solidarity, furthering the ideals of health justice, reciprocity, shared decision‐making, shared resources, shared responsibility, mutual trust, transparency, and mutual collective accountability. Examples of how the principles may be applied are provided. We recommend that these principles should form the foundation of any mechanism that seeks to systematically advance justice, fairness and equity in genomics research in Africa and more broadly, global health and science equity
Accountability · Bioethics · Biology · Corporate governance · Data sharing · Economics · Engineering ethics · Genomics · Global health · Health care · Health equity · Management · Political science · Public relations · Sociology · CRISPR and Genetic Engineering · Ethics in Clinical Research · Law · Medicine · Viral Infections and Outbreaks Research · Genetics
Genomics is failing on diversity
Ubuntu philosophy and the consensus regarding incidental findings in genomic research
Genomics governance
Global Health Justice and Governance
Global health ethics
Justice in International Clinical Research
Global health governance as shared health governance
Investing in Justice
Linking Research to Global Health Equity
Exploring the feasibility of theory synthesis
Governance of global health research consortia
| Citations per year | 1.33 |
|---|---|
| Citation span | 2023 - 2026 (4) |
| Highly cited | No |