Skip to main content

ETHNOS_APP

Home • Search • Journals • List 0

On the moral (in)equivalence of human embryos and stem cell-derived embryo models

Bibliographic Data

ID21515221
AuthorsNienke de Graeff (0000-0002-0045-4366, Department of Medical Ethics and Health Law, Leiden University Medical Center, Leiden, The Netherlands), Lien De Proost (0000-0003-0983-8865, Department of Medical Ethics and Health Law, Leiden University Medical Center, Leiden, The Netherlands)
Year2025
Volume51
Issue12
Pages853-855
Publication date2025-12-01
Open AccessNo
TypeARTICLE
VenueJournal of Medical Ethics (JOURNAL)
Journal identifiersISSN: 0306-6800 • E-ISSN: 1473-4257
PublisherBMJ (PUBLISHER • GB)
DOI10.1136/jme-2025-110866
PMID40393700
OpenAlexW4410555210
LanguageEN
Citations received2
References cited7

Gyngell et al argue that no intrinsic differences exist between stem cell-derived embryo models (SCEMs) and embryos derived from fertilisation that would justify attributing a higher moral status to the latter. Consequently, they claim there is no ethical rationale for treating SCEMs differently from embryos and contend that endorsing SCEMs as having moral advantages over embryos constitutes an obfuscation. In this commentary, we challenge the assertion that human SCEMs and embryos are morally equivalent by painting a more nuanced picture of the moral value of (different kinds of) SCEMs and embryos. First, we highlight the diversity among SCEMs, noting that different types of SCEMs need not be morally equivalent. This point is illustrated by taking a closer look at their potentiality, a property often considered relevant to moral status. Second, we observe that Gyngell et al , like much of the broader debate, primarily concentrate on the direct moral status of SCEMs in their analysis of the moral (in)equivalence with embryos. We argue that a comprehensive moral evaluation should encompass different types of moral value, evaluating not only direct moral status but also relational, symbolic and instrumental value. Ultimately, we suggest that the real obfuscation lies not in endorsing SCEMs as having moral advantages over embryos but rather in the overemphasis on direct moral status and the binary thinking about the moral (in)equivalence of embryos versus SCEMs that dominates these discussions

Assertion · Epistemology · Moral disengagement · Moral reasoning · Sociology · Biomedical Ethics and Regulation · Computer Science · Neuroethics, Human Enhancement, Biomedical Innovations · Philosophy · Pluripotent Stem Cells Research · Psychology · Social Psychology

  • Moral equivalence and the grounds of moral status in stem cell-derived embryo models

    Johnny Sakr, Johnny M Sakr•Journal of Medical Ethics•2026

  • Is the integrated/non-integrated distinction for embryo models really obsolete

    Hafez Ismaili M’hamdi•Journal of Medical Ethics•2025

  • Potentiality switches and epistemic uncertainty

    Open Access•Ana M Pereira Daoud, Wybo Dondorp et al.•Medicine Health Care and Philosophy•2024

  • Stem cell-derived embryo models

    Christopher Gyngell, Fiona Lynch et al.•Journal of Medical Ethics•2025

Citations per year2
Citation span2025 - 2026 (2)
Highly citedNo

Tools

Open DOIOpen Access
Ethnos_APP • Open Source Project • MIT License • Frontend v2.0.0 • Privacy and Cookies • API Documentation: api.ethnos.app/docs • API Source Code: GitHub • DOI: 10.5281/zenodo.17049435 • Frontend Source Code: GitHub • DOI: 10.5281/zenodo.17050053 • cruz.rio.br • Expectantes Misericordiae