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Xenotransplantation Clinical Trials and Equitable Patient Selection

Bibliographic Data

ID21598163
AuthorsChris Bobier (0000-0003-4194-4721, Saint Mary's University of Minnesota, corresponding author), Daniel Rodger (0000-0002-2121-7167, London South Bank University)
Year2024
Volume33
Issue3
Pages425-434
Publication date2024-07-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueCambridge Quarterly of Healthcare Ethics (JOURNAL)
Journal identifiersISSN: 0963-1801 • E-ISSN: 1469-2147
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s096318012300052x
PMID37795637
OpenAlexW4387357563
LanguageEN
Citations received3
References cited30

Xenotransplant patient selection recommendations restrict clinical trial participation to seriously ill patients for whom alternative therapies are unavailable or who will likely die while waiting for an allotransplant. Despite a scholarly consensus that this is advisable, we propose to examine this restriction. We offer three lines of criticism: (1) The risk–benefit calculation may well be unfavorable for seriously ill patients and society; (2) the guidelines conflict with criteria for equitable patient selection; and (3) the selection of seriously ill patients may compromise informed consent. We conclude by highlighting how the current guidance reveals a tension between the societal values of justice and beneficence

Clinical trial · Intensive care medicine · Xenotransplantation · Anesthesia and Neurotoxicity Research · Computer Science · Medicine · Organ Transplantation Techniques and Outcomes · Xenotransplantation and immune response · Artificial Intelligence · Internal Medicine · Transplantation

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Unique citing works3
Citations per year3
Citation span2025 - 2026 (2)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 3

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