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Attitudes and Intentions toward Use of HIV Pre-Exposure Prophylaxis (PrEP) among Adults Receiving Treatment for Opioid Use

Bibliographic Data

ID21645162
AuthorsTornia J S Wyllie (Division of Adolescent and Transition Medicine, Cincinnati Children’s Hospital Medical Center), Tornia Wyllie (Cincinnati Children's Hospital Medical Center), Jennifer Brown (0000-0001-7418-1172, University of Cincinnati), Jennifer L Brown (0000-0002-6683-0053, Purdue University West Lafayette), Andrea Meisman (0000-0002-9594-8085, Division of Adolescent and Transition Medicine, Cincinnati Children’s Hospital Medical Center), Nadia Bayyari (University of Cincinnati), Colleen Mangeot (Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital Medical Center), Qin Sun (0000-0003-4584-2781, Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital Medical Center), Tanya L Kowalczyk Mullins (Division of Adolescent and Transition Medicine, Cincinnati Children’s Hospital Medical Center, corresponding author)
Year2024
Volume59
Issue3
Pages369-379
Publication date2024-02-23
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueSubstance Use & Misuse (JOURNAL)
Journal identifiersISSN: 1082-6084 • E-ISSN: 1532-2491
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/10826084.2023.2275556
PMID37917069
OpenAlexW4388220164
LanguageEN
References cited66

Background: Although pre-exposure prophylaxis (PrEP) prevents HIV, little is known about PrEP awareness and factors associated with intention to take PrEP among people with opioid use disorder (OUD). Methods: HIV-negative adults recruited from an outpatient treatment program in Cincinnati, Ohio completed self-administered surveys. Items derived from literature and health behavioral theory included demographics, sexual and drug use behaviors, HIV prevention practices, PrEP knowledge, and attitudes toward PrEP. Primary outcomes were 1) intention to ask a clinician about PrEP and 2) intention to accept PrEP if recommended by a clinician. Outcomes were dichotomized into higher vs. lower intention for analyses in logistic regression models. Results: Among 198 participants, 60.3% reported past injection drug use. Among 58 participants (29.3%) meeting criteria for PrEP, 24% were aware of PrEP, 15.5% had discussed it with a clinician, and 5% had taken it. Factors associated with intention to ask a clinician about PrEP included being somewhat confident about consistent condom use (p < 0.01), motivation to comply with normative beliefs (p < 0.01), and reporting that PrEP fits very well (p < 0.01) and is easy to fit (p < 0.01) into current prevention practices. Factors associated with intention to accept PrEP if recommended by a clinician included motivation to comply with normative beliefs (p < 0.01) and PrEP being easy to fit into current prevention practices (p < 0.01). Conclusion: Among participants meeting indications for PrEP, only 24% were aware of it and few had taken it. Interventions that normalize PrEP and target incorporating PrEP into current prevention practices may improve uptake among individuals with OUD

Condom · Demographics · Family medicine · Logistic regression · Men who have sex with men · Normative · Pre-exposure prophylaxis · Psychiatry · Psychological intervention · Young adult · Clinical Psychology · Demography · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Sex work and related issues · Gerontology · Internal Medicine

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Highly citedNo

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