SRY-Positive 46, XX Testicular Disorder of Sexual Development With Leydig Cell Tumor
Bibliographic Data
The risk of a gonadal tumor is high in testicular disorder of sexual development (DSD) with the Y chromosome, but cases of DSD without the Y chromosome are extremely rare. We reported a gonadal tumor in a phenotypically male individual with 46, XX testicular DSD. A testicular tumor was incidentally found in a 32-year-old phenotypic male who was presented to the hospital with male infertility. A diagnosis of 46, XX testicular DSD was made by the presentation of karyotype analysis of 46, XX with the sex-determining region of the Y chromosome (SRY) positive and gonadal tissue without female gonads. Surgery was performed due to a gradually growing tumor. The partial orchidectomy was performed with the diagnosis of a benign Leydig cell tumor in frozen biopsy
Andrology · Biology · Chromosome · Gene · Gynecology · Hormone · Infertility · Karyotype · Leydig cell · Leydig Cell Tumor · Male infertility · Pregnancy · Testis determining factor · Y chromosome · Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities · Medicine · Sexual Differentiation and Disorders · Testicular diseases and treatments · Endocrinology · Genetics
| Citations per year | 0.5 |
|---|---|
| Citation span | 2024 - 2024 (1) |
| Highly cited | No |