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Association between the extension of smoke-free legislation and incident acute myocardial infarctions in Singapore from 2010 to 2019

An interrupted time-series analysis

Bibliographic Data

ID21880558
AuthorsJamie Sin Ying Ho (0000-0002-1180-6902, National University Hospital), Andrew Fu Wah Ho (0000-0003-4338-3876, SingHealth), Eric Jou (University of Cambridge), Nan Liu (0009-0003-4309-5513, Duke-NUS Medical School), Huili Zheng (0000-0002-3976-0088, Health Promotion Board), Joel Aik (0000-0002-2851-9424, National Environment Agency, corresponding author)
Year2023
Volume8
Issue10
Pagese012339
Publication date2023-10-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueBMJ Global Health (JOURNAL)
Journal identifiersISSN: 2059-7908 • E-ISSN: 2059-7908
PublisherBMJ (PUBLISHER • GB)
DOI10.1136/bmjgh-2023-012339
PMID37816537
OpenAlexW4387478103
LanguageEN
References cited40

BACKGROUND: We examined the association between smoke-free laws implemented in the outdoors and the common areas of residential apartment blocks and reported acute myocardial infarctions (AMI) in Singapore. METHODS: We used an interrupted time-series design and seasonal autoregressive integrated moving average models to examine the effect of the smoke-free law extensions in 2013 (common areas of residential blocks, covered pedestrian linkways, overhead bridges and within 5 m of bus stops), 2016 (parks) and 2017 (educational institutions, buses and taxis) on the monthly incidence rate of AMIs per 1 000 000 population. RESULTS: We included 133 868 AMI reports from January 2010 to December 2019. Post-2013, there was a decrease in the AMI incidence trend (β=-0.6 per month, 95%CI -1.0 to -0.29) and 2097 (95% CI 2094 to 2100) more AMIs may have occurred without the extension. There was a significant step-decline in male AMIs and a non-significant step-increase in female AMIs post-2013. Those 65 years and older experienced a greater decline to the postlegislation 2013 trend (β=-5.9, 95% CI -8.7 to -3.1) compared with those younger (β=-0.4, 95% CI -0.6 to -0.2), while an estimated 19 591 (15 711 to 23472) additional AMI cases in those 65 years and above may have occurred without the extension. We found a step-increase in monthly AMI incidence post-2016 (β=14.2, 95%CI 3.3 to 25.0). CONCLUSION: The 2013 smoke-free law extension to residential estates and other outdoor areas were associated with a decline in AMIs and those above the age of 65 years and men appeared to be major beneficiaries. Additional epidemiological evidence is required to support the expanded smoke-free legislation to parks, educational institutions, buses and taxis

Environmental health · Interrupted time series · Population · Rate ratio · Air Quality and Health Impacts · Demography · Injury Epidemiology and Prevention · Medicine · Smoking Behavior and Cessation

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