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Epidemiological Trends of Coronavirus Disease 2019 in Sierra Leone From March 2020 to October 2021

Bibliographic Data

ID22068377
AuthorsZhiguo Liu (0000-0002-8485-7356, National Institute for Communicable Disease Control and Prevention), Liping Gao (0000-0001-8542-6171, National Institute for Viral Disease Control and Prevention), Chuizhao Xue (National Institute for Parasitic Diseases), Chunchun Zhao (0000-0002-6698-727X, National Institute for Communicable Disease Control and Prevention), Tiezhu Liu (0000-0003-3989-1819, National Institute for Viral Disease Control and Prevention), Alie Tia, Lili Wang (0000-0002-0082-8487, Chinese Center For Disease Control and Prevention), Junlin Sun (0000-0003-3149-9038, Chinese Center For Disease Control and Prevention, corresponding author), Junling Sun, Zhenjun Li (0000-0003-4846-5440, National Institute for Communicable Disease Control and Prevention, corresponding author), Doris Harding (Ministry of Health and Sanitation, corresponding author)
Year2022
Volume10
Pages949425-949425
Publication date2022-06-29
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.949425
PMID35844842
OpenAlexW4283711035
LanguageEN
Citations received3
References cited38

Coronavirus disease 2019 (COVID-19), a serious public health challenge the world over, has led to significant health concerns in Sierra Leone. In the present study, epidemic indices, such as the number of cases, positivity rate, reproduction rate (R0), case fatality rate (CFR), age, and sex, were used to characterize the epidemiological trends of COVID-19. As of October 31, 2021, a total of 6,398 cases and 121 related deaths had been confirmed. The total number of COVID-19 reverse transcription polymerase chain reaction (RT-PCR) tests conducted to October 31, 2021, was 249,534, and the average positivity rate was 2.56%. Three waves of COVID-19 were recorded, occurring during weeks 15–46 in 2020 (2,369 cases), week 47 in 2020 to week 16 in 2021 (1,665 cases), and weeks 17–43 in 2021 (2,364 cases), respectively. Remarkably, there was no increase in the numbers of confirmed COVID-19 cases despite rising test numbers throughout the three waves. Moreover, three high R0 values were observed before each wave. The number of positive cases significantly correlated with positive numbers of international arrivals ( P < 0.01), deaths ( P < 0.01), and the positivity rate of tested samples ( P < 0.01). Moreover, all of the deaths occurred during the peak of the three waves. Our results indicate that there was a low level of COVID-19 epidemic in Sierra Leone and that COVID-19's introduction led to local transmission. It is vital to fight against the spread of SARS-CoV-2 from the source of origin by strengthening testing and management of people entering the country. Our findings will provide important clues for expanding sample screening and will contribute to the reasonable allocation of medical resources

Attack rate · Basic reproduction number · Case fatality rate · Coronavirus · Disease · Environmental health · Mortality rate · Pathology · Population · Public health · Sierra leone · Socioeconomics · COVID-19 diagnosis using AI · COVID-19 epidemiological studies · Demography · Immune responses and vaccinations · Medicine · Epidemiology · Internal Medicine · Virology

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Unique citing works3
Citations per year0,75
Citation span2022 - 2025 (4)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 3

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