Associations between depression and the incident risk of obesity in southwest China

A community population prospective cohort study

Bibliographic Data

ID22069220
AuthorsTao Liu (0000-0001-5480-2568, Guizhou Center for Disease Control and Prevention), Bo Wu (0000-0002-8911-1625, Fudan University), Yuntong Yao (Guizhou Center for Disease Control and Prevention), Yun Chen (0000-0001-5123-1624, Fudan University), Jie Zhou (0000-0003-2319-8673, Guizhou Center for Disease Control and Prevention), Kelin Xu (0000-0002-6788-4256, Fudan University), Na Wang (0000-0003-1102-8220, Fudan University), Chaowei Fu (0000-0003-0966-8552, Fudan University, corresponding author)
Year2023
Volume11
Pages1103953-1103953
Publication date2023-01-19
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1103953
PMID36741957
OpenAlexW4317518421
LanguageEN
Citations received1
References cited46

Objective: This study aimed to describe the incidence of obesity and investigate associations between depression and the risk of incident obesity among residents in Southwest China. Methods: A 10-year prospective cohort study of 4,745 non-obese adults was conducted in Guizhou, southwest China from 2010 to 2020. Depression was assessed by the Patient Health Questionnaire-9 (PHQ-9) while the obesity was identified by waist circumference (WC) and/or body mass index (BMI). Cox proportional hazard models were used to estimate hazard ratios (HR), and 95% confidence intervals (CIs) of depression and incident obesity. Results: A total of 1,115 incident obesity were identified over an average follow-up of 7.19 years, with an incidence of 32.66 per 1,000 PYs for any obesity, 31.14 per 1,000 PYs and 9.40 per 1,000 PYs for abdominal obesity and general obesity, respectively. After adjustment for potential confounding factors, risks of incident abdominal obesity for subjects with minimal (aHR: 1.22, 95% CI: 1.05, 1.43), and mild or more advanced depression (aHR: 1.27, 95% CI: 1.01, 1.62) were statistically higher than those not depressed, while there was no significant association with incident general obesity. The risks of any incident obesity among subjects with minimal (aHR: 1.21, 95% CI: 1.04, 1.40), mild or more advanced depression (aHR: 1.30, 95% CI: 1.03, 1.64) were significantly higher than those not depressed and positive association was found for PHQ score per SD increase (aHR: 1.07, 95%CI: 1.01, 1.13), too. The association was stronger significantly in Han Chinese (minimal: aHR: 1.27, 95% CI: 1.05, 1.52; mild or more advanced: aHR: 1.70, 95% CI: 1.30, 2.21) and farmers (minimal: aHR: 1.64, 95% CI: 1.35, 2.01; mild or more advanced: aHR: 1.82, 95% CI: 1.32, 2.51). Conclusion: Depression increased the risk of incident obesity among adults in Southwest China, especially among Han Chinese and farmers. This finding suggests that preventing and controlling depression may benefit the control of incident obesity

Abdominal obesity · Body mass index · Cohort · Cohort study · Confidence interval · Confounding · Environmental health · Hazard ratio · Obesity · Population · Proportional hazards model · Prospective cohort study · Waist · Bariatric Surgery and Outcomes · Cardiac Health and Mental Health · Demography · Diabetes, Cardiovascular Risks, and Lipoproteins · Medicine · Internal Medicine

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