Hypertension outcomes in a fragile setting
Predictors of blood pressure reduction and control in the Central African Republic
Bibliographic Data
| ID | 22069480 |
|---|---|
| Authors | Anna Maria Doro Altan (Link Campus University), Boris Tchenebou (University of Bangui), Kevine Iffio (University of Bangui), Gabriella Bortolot (Presidio Ospedaliero), Stefano Orlando (0000-0001-9706-4075, University of Rome Tor Vergata), Giovanni Guidotti (0000-0002-8462-2901, ASL Roma), Sandro Petrolati (IRCCS San Camillo Hospital), Pierre Somsé (University of Bangui), Fausto Ciccacci (0000-0003-0262-707X, University of Rome Tor Vergata, corresponding author) |
| Year | 2025 |
| Volume | 13 |
| Pages | 1664189-1664189 |
| Publication date | 2025-10-29 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2025.1664189 |
| PMID | 41235217 |
| OpenAlex | W4415646898 |
| Language | EN |
| Citations received | 2 |
| References cited | 22 |
Background Hypertension is a leading contributor to cardiovascular disease and early mortality, and its impact is growing rapidly in low-income countries. In the Central African Republic, the condition represents a major and under-addressed health problem. This study examines the outcomes of hypertension care in Bangui, focusing on factors influencing blood pressure control and reduction (CAR). Methods This cross-sectional study analyzed clinical records of hypertensive patients receiving care in Bangui. Demographic and clinical data were collected at baseline and at the most recent follow-up (October-November 2024) to identify factors associated with BP control (<140/90 mmHg) and reduction (decrease of ≥20 mmHg in systolic or ≥10 mmHg in diastolic BP). Results We included 656 patients (69% female, median age 59 years). BP control and clinically significant BP reduction were achieved in 39.5 and 86.7% of patients. Diabetes was an independent predictor of lower BP control (OR = 0.36; 95%CI:0.25–0.52; p < 0.001) and lower BP reduction (OR = 0.56; 95%CI:0.35–0.88; p = 0.012). Chronic kidney disease was associated with lower BP reduction (OR = 0.10; 95%CI:0.02–0.52; p = 0.006). Higher baseline hypertension correlated with BP reduction (Grade 3 hypertension: OR = 88.3; 95%CI:23.4–587; p < 0.001). Older age was associated with BP reduction (OR = 1.16; 95%CI:1.04–1.29; p = 0.007). Conclusion In Bangui, structured hypertension care proved feasible and led to significant BP reductions, although target control rates remained low, particularly in patients with diabetes and CKD. Strengthening follow-up and access to tailored treatment could improve outcomes in this fragile setting
Blood pressure · Case-control study · Diabetes mellitus · Health care · Patient care · Blood Pressure and Hypertension Studies · Global Maternal and Child Health · Global Public Health Policies and Epidemiology
| Citations per year | 2 |
|---|---|
| Citation span | 2026 - 2026 (1) |
| Highly cited | No |