Transmission of tuberculosis in an incarcerated population during the subclinical period

A cross-sectional study in Qingdao, China

Bibliographic Data

ID22073077
AuthorsZhongdong Wang (0000-0002-6006-9566, Qingdao Municipal Center for Disease Control and Prevention), Haoran Li (0000-0002-2453-1995, Capital Medical University), Song Song (0000-0002-7618-5692, Qingdao Municipal Center for Disease Control and Prevention), Haiyan Sun (0000-0002-6344-9724, Qingdao Municipal Center for Disease Control and Prevention), Xiaoqi Dai (0000-0002-5065-7989, Qingdao Municipal Center for Disease Control and Prevention), Meng Chen (0000-0003-4503-5226, Qingdao Municipal Center for Disease Control and Prevention), Honghong Xu (0000-0002-0476-6383, Qingdao Municipal Center for Disease Control and Prevention), Huaqiang Zhang (0000-0002-6566-3468, Qingdao Municipal Center for Disease Control and Prevention, corresponding author), Yu Pang (0000-0002-0379-1085, Capital Medical University, corresponding author)
Year2023
Volume11
Pages1098519-1098519
Publication date2023-01-25
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1098519
PMID36761133
OpenAlexW4317910792
LanguageEN
References cited18

Objectives: As a closed gathering place, prison is the cradle of tuberculosis (TB) outbreak. Therefore, the analysis of the prevalence rate and risk factors of latent tuberculosis infection (LTBI) in prison will be a necessary measure to intervene in the spread of tuberculosis. Methods: In this study, we consecutively recruited 506 adult prisoners in Qingdao to carry out this cross-sectional study. TB and LTBI were screened by IGRA, X-ray, X-pert, sputum smear and culture. Results: A total of 17 TB, 101 LTBI and 388 HC were identified, with an infection rate of 23.32% (118/506) and a TB incidence rate of 3282/100,000 population. Age, malnutrition and inmates living with TB prisoners were risk factors for LTBI. Additionally, most TB cases (70.59%, 12/17) were subclinical tuberculosis (STB), contributing significantly to TB transmission. Conclusion: Our results demonstrate that the transmission efficiency of asymptomatic patients is not essentially different from that of symptomatic patients, indicating that TB transmission occurs during the subclinical period. Our findings highlight the need to strengthen active case-finding strategies to increase TB case detection in this population

Asymptomatic · Cross-sectional study · Environmental health · Pathology · Population · Sputum · Subclinical infection · Tuberculosis · Diagnosis and treatment of tuberculosis · Infectious Diseases and Tuberculosis · Medicine · Tuberculosis Research and Epidemiology · Internal Medicine · Pediatrics

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