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Simulating Transmission Scenarios of the Delta Variant of Sars-CoV-2 in Australia

Bibliographic Data

ID22073758
AuthorsSheryl L Chang (0000-0002-6119-828X, The University of Sydney), Oliver M Cliff (0000-0001-5041-4090, The University of Sydney), Cameron Zachreson (0000-0002-0578-4049, The University of Sydney), Mikhail Prokopenko (0000-0002-4215-0344, The University of Sydney, corresponding author)
Year2022
Volume10
Pages823043-823043
Publication date2022-02-24
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.823043
PMID35284395
OpenAlexW3214775149
LanguageEN
Citations received6
References cited34

An outbreak of the Delta (B.1.617.2) variant of SARS-CoV-2 that began around mid-June 2021 in Sydney, Australia, quickly developed into a nation-wide epidemic. The ongoing epidemic is of major concern as the Delta variant is more infectious than previous variants that circulated in Australia in 2020. Using a re-calibrated agent-based model, we explored a feasible range of non-pharmaceutical interventions, including case isolation, home quarantine, school closures, and stay-at-home restrictions (i.e., “social distancing.”) Our modelling indicated that the levels of reduced interactions in workplaces and across communities attained in Sydney and other parts of the nation were inadequate for controlling the outbreak. A counter-factual analysis suggested that if 70% of the population followed tight stay-at-home restrictions, then at least 45 days would have been needed for new daily cases to fall from their peak to below ten per day. Our model predicted that, under a progressive vaccination rollout, if 40–50% of the Australian population follow stay-at-home restrictions, the incidence will peak by mid-October 2021: the peak in incidence across the nation was indeed observed in mid-October. We also quantified an expected burden on the healthcare system and potential fatalities across Australia

Biology · Disease · Economics · Environmental health · Geography · Outbreak · Pandemic · Population · Psychological intervention · Quarantine · Social distance · Socioeconomics · Sociology · Telecommunications · Vaccination · Computer Science · COVID-19 epidemiological studies · Demography · Medicine · SARS-CoV-2 and COVID-19 Research · Vaccine Coverage and Hesitancy · Virology

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  • Phase-wise evaluation and optimization of non-pharmaceutical interventions to contain the Covid-19 pandemic in the U.S

    Open Access•Xiao Zhou, Xiaofang Zhou et al.•Frontiers in Public Health•2023

  • Simulating Transmission Scenarios of the Delta Variant of Sars-CoV-2 in Australia

    Open Access•Sheryl L Chang, Oliver M Cliff et al.•Frontiers in Public Health•2022

  • Qualitative Insights into How Older People and Their Families Use Telecommunications during a Pandemic to Alleviate Social Isolation

    Cheong Loke, Burkhard C Wünsche•Journal of Intergenerational…•2023

  • An Introduction to the Bootstrap

    Bradley Efron, Robert Tibshirani et al.•Introduction to the Bootstrap•1994

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    Stephen A Lauer, Kyra H Grantz et al.•Annals of Internal Medicine•2020

  • Virological assessment of hospitalized patients with Covid-2019

    Open Access•Roman Wölfel, Victor M Corman et al.•Nature•2020

  • Presymptomatic Sars-CoV-2 Infections and Transmission in a Skilled Nursing Facility

    Melissa M Arons, Melissa Arons et al.•New England Journal of Medicine•2020

  • Estimating clinical severity of Covid-19 from the transmission dynamics in Wuhan, China

    Open Access•Joseph T Wu, Kathy Leung et al.•Nature Medicine•2020

  • Modelling transmission and control of the Covid-19 pandemic in Australia

    Open Access•Sheryl L Chang, Nathan Harding et al.•Nature Communications•2020

  • Quantifying Sars-CoV-2 transmission suggests epidemic control with digital contact tracing

    Open Access•Luca Ferretti, Chris Wymant et al.•Science•2020

  • Simulating Transmission Scenarios of the Delta Variant of Sars-CoV-2 in Australia

    Open Access•Sheryl L Chang, Oliver M Cliff et al.•Frontiers in Public Health•2022

Citations per year1.5
Citation span2022 - 2023 (2)
Highly citedNo

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