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Rubella Serosurvey Among Future Healthcare Workers

Bibliographic Data

ID22076320
AuthorsAndrea Trevisan (0000-0002-0764-1084, University of Padua, corresponding author), Paola Mason (0000-0003-3941-6698, University of Padua), Annamaria Nicolli (University of Padua), Stefano Maso (0000-0002-7386-9335, University of Padua), Chiara Bertoncello (0000-0003-4040-8601, University of Padua)
Year2021
Volume9
Pages741178-741178
Publication date2021-09-13
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2021.741178
PMID34589465
OpenAlexW3201094163
LanguageEN
Citations received1
References cited21

Objective: Rubella is a very diffusive but relatively benign infectious disease unless contracted during pregnancy, when it causes congenital rubella syndrome. The aim of this research was to determine the prevalence and titer of antirubella antibodies in a population of future healthcare workers (students at the school of medicine). Methods: The cohort consisted of 11,022 students who underwent antibody analysis after the presentation of a vaccine certificate. Results: Vaccination compliance was very high, particularly in younger students (born after 1995), reaching almost 100% (at least one dose). Unvaccinated students born before 1990 had high seropositivity (>95%), but this percentage dropped to zero among the youngest students. Variables affecting antibody titer included year of birth and sex. Considering only vaccinated students, a greater antibody response was observed if the vaccine was administered between 8 and 10 years of age. Female sex was associated with more significant ( p < 0.0001) positivity and higher antibody titer after one and two doses. However, this difference appeared less consistent in relation to year of birth. Conclusions: The studied population exhibited excellent vaccination compliance, high seropositivity, and high antibody titer. Vaccine and immune coverage were higher than what is deemed necessary to achieve herd immunity

Antibody · Antibody titer · Environmental health · Health care · Herd immunity · Measles · Obstetrics · Population · Pregnancy · Rubella · Rubella vaccine · Titer · Vaccination · Medicine · Rabies epidemiology and control · Syphilis Diagnosis and Treatment · Virology and Viral Diseases · Immunology · Pediatrics

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    Open Access•Luca Coppeta, Cristiana Ferrari et al.•International Journal of…•2020

Citations per year1
Citation span2026 - 2026 (1)
Highly citedNo

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