Omicron variant and pulmonary involvements
A chest imaging analysis in asymptomatic and mild Covid-19
Bibliographic Data
| ID | 22082583 |
|---|---|
| Authors | Peiben Liu (Nanjing University of Chinese Medicine), Kejun Cao (Jiangsu Province Hospital), Guanqun Dai (0000-0002-0256-0605, Jiangsu Province Hospital), Tingzhen Chen (0000-0001-6634-2757, Jiangsu Province Hospital), Yifan Zhao (0000-0003-2383-5724, Jiangsu Province Hospital), Hai Xu (0000-0003-4644-9033, Jiangsu Province Hospital), Xiaoquan Xu, Xiao‐Quan Xu (0000-0001-5493-5256, Jiangsu Province Hospital), Quan Cao (0000-0002-1566-8850, Jiangsu Province Hospital), Yiyang Zhan (Jiangsu Province Hospital), Xiangrong Zuo (0000-0002-5542-6362, Jiangsu Province Hospital, corresponding author) |
| Year | 2024 |
| Volume | 12 |
| Pages | 1325474-1325474 |
| Publication date | 2024-07-04 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2024.1325474 |
| PMID | 39035180 |
| OpenAlex | W4400335522 |
| Language | EN |
| References cited | 40 |
Objectives To identify clinical characteristics and risk factors for pulmonary involvements in asymptomatic and mildly symptomatic patients infected with SARS-CoV-2 Omicron variant by chest imaging analysis. Methods Detailed data and chest computed tomography (CT) imaging features were retrospectively analyzed from asymptomatic and mildly symptomatic patients infected with Omicron between 24 April and 10 May 2022. We scored chest CT imaging features and categorized the patients into obvious pulmonary involvements (OPI) (score > 2) and not obvious pulmonary involvements (NOPI) (score ≤ 2) groups based on the median score. The risk factors for OPI were identified with analysis results visualized by nomogram. Results In total, 339 patients were included (145 were male and 194 were female), and the most frequent clinical symptoms were cough (75.5%); chest CT imaging features were mostly linear opacities (42.8%). Pulmonary involvements were more likely to be found in the left lower lung lobe, with a significant difference in the lung total severity score of the individual lung lobes ( p 8d) [OR = 1.842, 95% CI (1.104–3.073); p = 0.019], and pulmonary diseases [OR = 4.698, 95% CI (1.159–19.048); p = 0.03] as independent OPI risk factors. Conclusion Asymptomatic and mildly symptomatic patients infected with Omicron had pulmonary involvements which were not uncommon. Potential risk factors for age stratification, prolonged NCT, and pulmonary diseases can help clinicians to identify OPI in asymptomatic and mildly symptomatic patients infected with Omicron
Asymptomatic · Confidence interval · Disease · Logistic regression · Lung · Odds ratio · Radiology · COVID-19 Clinical Research Studies · Long-Term Effects of COVID-19 · Medicine · SARS-CoV-2 and COVID-19 Research · Internal Medicine
| Highly cited | No |
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