Assessment of Financial Toxicity Among Patients With Advanced Lung Cancer in Western China
Bibliographic Data
| ID | 22089262 |
|---|---|
| Authors | Tianqi Xu (0000-0002-1027-4051, Xijing Hospital), Leidi Xu (Xijing Hospital), Hangtian Xi (Xijing Hospital), Yong Zhang (0000-0001-6711-5791, Jiujiang Maternal and Child Care Centres), Ying Zhou (0000-0001-7335-5601, Xijing Hospital), Ning Chang (0000-0002-5244-1858, Xijing Hospital), Wenhui Yang (0009-0003-7692-7777, Xijing Hospital), Yan Zhang (0000-0001-8460-2671, Jiujiang Maternal and Child Care Centres), Ming Wang (0000-0001-8056-4604, Xijing Hospital), Qing Ju (Xijing Hospital), Xuemin Yang (0000-0002-1534-4055, Xijing Hospital), Xiangxiang Chen (0000-0002-2875-1055, Xijing Hospital), Yinggang Che (Xijing Hospital), Fulin Chen (0000-0001-9956-7194, Northwest University), Shuoyao Qu (Xijing Hospital, corresponding author), Jian Zhang (0000-0001-7681-8747, Northwest University, corresponding author) |
| Year | 2022 |
| Volume | 9 |
| Pages | 754199-754199 |
| Publication date | 2022-01-12 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2021.754199 |
| PMID | 35096733 |
| OpenAlex | W4205202293 |
| Language | EN |
| Citations received | 2 |
| References cited | 23 |
Background: Lung cancer is the leading source of cancer-caused disability-adjusted life years. Medical cost burden impacts the well-being of patients through reducing income, cutting daily expenses, curtailing leisure activities, and depleting exhausting savings. The COmprehensive Score for Financial Toxicity (COST) was created and validated by De Souza and colleagues. Our study intends to measure the financial burdens of cancer therapy and investigate the link between financial toxicity and health-related quality of life (HRQoL) in an advanced lung cancer population. Methods: Patients aged ≥ 18 years with confirmed stage III to IV lung cancer were eligible. The COST questionnaire verified by de Souza et al. was used to identify financial toxicity. Multivariable linear regression analysis with log transformation univariate analysis and Pearson correlations were used to perform the analysis. Results: The majority of the patients (90.8%, n = 138/152) had an annual income of $50,000 ($7,775). The cohort's insurance situation was as follows: 64.5% of the cohort had social insurance, 20.4% had commercial insurance, and 22.0% had both. Patients who were younger age (50–59, P < 0.001), employed but on sick leave, and had lower income reported increased levels of financial toxicity ( P < 0.05). The risk factors for high financial toxicity: (i) younger age (50–59), (ii) <1 month of savings, and (iii) being employed but on sick leave. Increased financial toxicity is moderately correlated with a decrease in QoL. Conclusion: Poorer psychological status and specific demographics are linked to increased financial toxicity (lower COST). Financial toxicity has a modest relationship with HRQoL and may have a clear link with HRQoL measurements
Business · Cancer · Cohort · Environmental health · Lung cancer · Multivariate analysis · Population · Toxicity · Univariate analysis · Economic and Financial Impacts of Cancer · Health Systems, Economic Evaluations, Quality of Life · Medicine · Multiple and Secondary Primary Cancers · Finance · Internal Medicine
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| Citations per year | 2 |
|---|---|
| Citation span | 2025 - 2026 (2) |
| Highly cited | No |