Global burden of diarrhea disease in the older adult and its attributable risk factors from 1990 to 2021
A comprehensive analysis from the global burden of disease study 2021
Bibliographic Data
| ID | 22089435 |
|---|---|
| Authors | Wenzhuo Zhao (Xuzhou Medical College), Wen-Zhuo Zhao, Jingyi Wang (0000-0002-3036-5006, Xuzhou Medical College), Jing-Yi Wang, Min-Na Zhang, Minna Zhang (0000-0003-1567-3788, Xuzhou Medical College), Shang-Nong Wu (0000-0001-8843-8215, Xuzhou Medical College), Weijie Dai (0000-0003-2793-1588, Xuzhou Medical College), Wei-Jie Dai, Xiaozhong Yang (0000-0002-4887-5602, Xuzhou Medical College, corresponding author), Xiao-Zhong Yang, Hong-Gang Wang, Hong‐Gang Wang (0000-0003-0551-0571, Xuzhou Medical College, corresponding author) |
| Year | 2025 |
| Volume | 13 |
| Pages | 1541492-1541492 |
| Publication date | 2025-04-04 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2025.1541492 |
| PMID | 40255369 |
| OpenAlex | W4409166692 |
| Language | EN |
| References cited | 31 |
Introduction: Diarrhea disease among the older adult is an underappreciated global health issue despite its substantial burden. This study provides a comprehensive analysis of the epidemiological trends of diarrhea in individuals over 65 years, examining incidence, prevalence, mortality, and disability-adjusted life-years (DALYs) from 1990 to 2021. Methods: Utilizing data from the Global Burden of Diseases (GBD) 2021, this cross-sectional study assesses the older adult population across 204 countries and territories. The analysis includes metrics such as incidence, prevalence, mortality, DALYs, and estimated annual percentage changes (EAPCs), stratified by region, country, age, sex, and Sociodemographic Index (SDI). Results: A nearly 200% increase in incidence and prevalence was observed worldwide, with the highest rise in those over 95 years. Mortality and DALYs have declined, especially in the 65-69 age group. High SDI regions showed the largest increase in incidence rates and are the only areas with increasing mortality and DALYs trends. Unsafe water sources emerged as the primary risk factor for diarrhea-related deaths among the older adult. Discussion: The burden of diarrhea in the older adult has significantly increased, particularly in high-income regions, warranting targeted interventions. The positive correlation between EAPC and the Human Development Index underscores the need for improved water safety to mitigate the disease burden. This study's findings are crucial for shaping public health strategies and informing policy decisions regarding the older adult population
Burden of disease · Diarrhea · Disease · Disease burden · Environmental health · Global health · Pathology · Population · Psychological intervention · Public health · Child Nutrition and Water Access · Demography · Global Health and Epidemiology · Medicine · Viral gastroenteritis research and epidemiology · Epidemiology · Gerontology
Global age-sex-specific fertility, mortality, healthy life expectancy (Hale), and population estimates in 204 countries and territories, 1950–2019
The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990–2016
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021
Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases
Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021
Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrhoeal disease in children in low-income and middle-income settings
Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (Dalys), and healthy life expectancy (Hale) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021
Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016
Burden of disease from inadequate water, sanitation and hygiene for selected adverse health outcomes
Interventions to address deaths from childhood pneumonia and diarrhoea equitably
Drivers of the reduction in childhood diarrhea mortality 1980-2015 and interventions to eliminate preventable diarrhea deaths by 2030
Evolution of the World Health Organization’s programmatic actions to control diarrheal diseases
Application of exponential smoothing method and Sarima model in predicting the number of admissions in a third-class hospital in Zhejiang Province
| Citation velocity | historical |
|---|---|
| Highly cited | No |