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Burden of disease from inadequate water, sanitation and hygiene for selected adverse health outcomes

An updated analysis with a focus on low- and middle-income countries

Bibliographic Data

ID23331664
AuthorsAnnette Prüss-Üstün, Annette Prüss‐Üstün (0000-0001-6272-212X, World Health Organization, corresponding author), Jennyfer Wolf (0000-0002-4242-4149, World Health Organization), John Bartram (0000-0002-6542-6315, University of North Carolina at Chapel Hill), Jamie Bartram, T Clasen (0000-0003-4062-5788, Emory University), Oliver Cummings (0000-0002-5074-8709, London School of Hygiene & Tropical Medicine), Oliver Cumming, Matthew C Freeman (0000-0002-1517-2572, Emory University), Bruce Gordon (0000-0001-8760-9377, World Health Organization), Paul R Hunter, Paul Hunter (0000-0002-5608-6144, University of East Anglia), Kate Medlicott (World Health Organization), Richard B Johnston (World Health Organization), Richard Johnston (0000-0003-0051-1225)
Year2019
Volume222
Issue5
Pages765-777
Publication date2019-06-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Hygiene and Environmental Health (JOURNAL)
Journal identifiersISSN: 1438-4639 • E-ISSN: 1618-131X
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.ijheh.2019.05.004
PMID31088724
OpenAlexW2944592180
LanguageEN
Citations received108
References cited51

BACKGROUND: To develop updated estimates in response to new exposure and exposure-response data of the burden of diarrhoea, respiratory infections, malnutrition, schistosomiasis, malaria, soil-transmitted helminth infections and trachoma from exposure to inadequate drinking-water, sanitation and hygiene behaviours (WASH) with a focus on low- and middle-income countries. METHODS: For each of the analysed diseases, exposure levels with both sufficient global exposure data for 2016 and a matching exposure-response relationship were combined into population-attributable fractions. Attributable deaths and disability-adjusted life years (DALYs) were estimated for each disease and, for most of the diseases, by country, age and sex group separately for inadequate water, sanitation and hygiene behaviours and for the cluster of risk factors. Uncertainty estimates were computed on the basis of uncertainty surrounding exposure estimates and relative risks. FINDINGS: An estimated 829,000 WASH-attributable deaths and 49.8 million DALYs occurred from diarrhoeal diseases in 2016, equivalent to 60% of all diarrhoeal deaths. In children under 5 years, 297,000 WASH-attributable diarrhoea deaths occurred, representing 5.3% of all deaths in this age group. If the global disease burden from different diseases and several counterfactual exposure distributions was combined it would amount to 1.6 million deaths, representing 2.8% of all deaths, and 104.6 million DALYs in 2016. CONCLUSIONS: Despite recent declines in attributable mortality, inadequate WASH remains an important determinant of global disease burden, especially among young children. These estimates contribute to global monitoring such as for the Sustainable Development Goal indicator on mortality from inadequate WASH.

Adverse effect · Biology · Developing country · Disease burden · Environmental health · Hygiene · Low and middle income countries · Malaria · Malnutrition · Pathology · Population · Sanitation · Trachoma · Child Nutrition and Water Access · Global Maternal and Child Health · Immunology · Internal Medicine · Medicine · Parasites and Host Interactions

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Unique citing works108
Citations per year18
Citation span2020 - 2026 (7)
Citation velocitycurrent
Highly citedYes
Citation typesNeutral: 99
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