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Diagnostics for detection and surveillance of priority epidemic-prone diseases in Africa

An assessment of testing capacity and laboratory strengthening needs

Bibliographic Data

ID22090033
AuthorsAytenew Ashenafi (Africa Centres for Disease Control and Prevention, corresponding author), Olajumoke Sule (0000-0002-2659-2230, Health Protection Agency), Trevor Peter (Clinton Health Access Initiative), Silver Mashate (0009-0002-6294-7358, African Society for Laboratory Medicine), Osborn Otieno (Global Fund to Fight AIDS, Tuberculosis and Malaria), Abebaw Kebede (0000-0002-6154-7275, Africa Centres for Disease Control and Prevention), John Oio (Africa Centres for Disease Control and Prevention), Kekeletso Kao (0000-0001-8404-9714, FIND), Jane Carter (0000-0001-6304-1027, Amref Health Africa), Toni Whistler (0000-0002-7250-908X, Global Fund to Fight AIDS, Tuberculosis and Malaria), Nqobile Ndlovu (0000-0003-3377-2042, African Society for Laboratory Medicine), Yenew Kebede (0000-0001-7224-8628, Africa Centres for Disease Control and Prevention)
Year2024
Volume12
Pages1438334-1438334
Publication date2024-09-18
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2024.1438334
PMID39360262
OpenAlexW4402576622
LanguageEN
Citations received4
References cited15

In 2023, Africa experienced 180 public health emergencies, of which 90% were infectious diseases and 75% were related to zoonotic diseases. Testing capacity for epidemic-prone diseases is essential to enable rapid and accurate identification of causative agents, and for action to prevent disease spread. Moreover, testing is pivotal in monitoring disease transmission, evaluating public health interventions and informing targeted resource allocation during outbreaks. An online, self-assessment survey was conducted in African Union Member States to identify major challenges in testing for epidemic-prone diseases. The survey assessed current capacity for diagnosing priority epidemic-prone diseases at different laboratory levels. It explored challenges in establishing and maintaining testing capacity to improve outbreak response and mitigate public health impact. Survey data analysed diagnostic capacity for priority infectious diseases, diagnostic technologies in use, existing surveillance programmes and challenges limiting diagnostic capacity, by country. The survey result from 15 Member States who responded to the survey, showed high variability in testing capacity and technologies across countries and diverse factors limiting testing capacity for certain priority diseases like dengue and Crimean-Congo haemorrhagic fever. At the same time diagnostic capacity is better for coronavirus disease 2019 (COVID-19), polio, and measles due to previous investments. Unfortunately, many countries are not utilizing multiplex testing, despite its potential to improve diagnostic access. The challenges of limited laboratory capacity for testing future outbreaks are indeed significant. Recent disease outbreaks in Africa have underscored the urgent need to strengthen diagnostic capacity and introduce cost-effective technologies. Small sample sizes and differing disease prioritisation within each country limited the analysis. These findings suggest the benefits of evaluating laboratory testing capacity for epidemic-prone diseases and highlight the importance of effectively addressing challenges to detect diseases and prevent future pandemics

Business · Capacity building · Disease · Disease surveillance · Economic growth · Environmental health · International Health Regulations · Measles · Outbreak · Poliomyelitis · Public health · Vaccination · Medicine · Viral Infections and Outbreaks Research · Viral Infections and Vectors · Zoonotic diseases and public health · Virology

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    Open Access•Pratik Sharma, Supriya D Mahajan et al.•PLOS Global Public Health•2026

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Unique citing works4
Citations per year4
Citation span2025 - 2026 (2)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 4

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