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Elucidating the Relationship Between Insomnia, Sex, and Cardiovascular Disease

Bibliographic Data

ID22157683
AuthorsRebecca Leeds (Columbia University Irving Medical Center), Ari Shechter (0000-0001-8243-0247, Columbia University Irving Medical Center), Carmela Alcántara (0000-0002-6460-3842, Columbia University), Brooke Aggarwal (0000-0002-6199-864X, Columbia University Irving Medical Center), John Usseglio (0000-0003-3184-4751, Columbia University Irving Medical Center), Marwah Abdalla (0000-0002-2725-505X, Columbia University Irving Medical Center), Nathalie Moise (0000-0002-5660-5573, Columbia University Irving Medical Center)
Year2020
Volume4
Pages247028972098001
Publication date2020-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueGender and the Genome (JOURNAL)
Journal identifiersISSN: 2470-2897 • E-ISSN: 2470-2900
PublisherThe Foundation for Gender-Specific Medicine, Inc (PUBLISHER)
DOI10.1177/2470289720980018
OpenAlexW3115331725
LanguageEN
References cited121

Sex differences in cardiovascular disease (CVD) mortality have been attributed to differences in pathophysiology between men and women and to disparities in CVD management that disproportionately affect women compared to men. Similarly, there has been investigation of differences in the prevalence and presentation of insomnia attributable to sex. Few studies have examined how sex and insomnia interact to influence CVD outcomes, however. In this review, we summarize the literature on sex-specific differences in the prevalence and presentation of insomnia as well as existing research regarding the relationship between insomnia and CVD outcomes as it pertains to sex. Research to date indicate that women are more likely to have insomnia than men, and there appear to be differential associations in the relation between insomnia and CVD by sex. We posit potential mechanisms of the relationship between sex, insomnia and CVD, discuss gaps in the existing literature, and provide commentary on future research needed in this area. Unraveling the complex relations between sex, insomnia, and CVD may help to explain sex-specific differences in CVD, and identify sex-specific strategies for promotion of cardiovascular health. Throughout this review, terms “men” and “women” are used as they are in the source literature, which does not differentiate between sex and gender. The implications of this are also discussed

Disease · Insomnia · Psychiatry · Sex characteristics · Circadian rhythm and melatonin · Clinical Psychology · Medicine · Obesity, Physical Activity, Diet · Psychology · Sleep and related disorders · Gerontology · Internal Medicine

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