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Moving back to the future of big data-driven research

Reflecting on the social in genomics

Bibliographic Data

ID22233232
AuthorsMelanie Goisauf (0000-0002-3909-8071, University of Vienna, corresponding author), Kaya Akyüz (0000-0002-2444-2095, University of Vienna, corresponding author), Gillian M Martin (0000-0002-5281-8117, University of Malta)
Year2020
Volume7
Issue1
Publication date2020-08-04
Open AccessYes
TypeARTICLE
VenueHumanities and Social Sciences Communications (JOURNAL)
Journal identifiersISSN: 2662-9992 • E-ISSN: 2662-9992
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1057/s41599-020-00544-5
OpenAlexW3047348076
LanguageEN
Citations received6
References cited58

With the advance of genomics, specific individual conditions have received increased attention in the generation of scientific knowledge. This spans the extremes of the aim of curing genetic diseases and identifying the biological basis of social behaviour. In this development, the ways knowledge is produced have gained significant relevance, as the data-intensive search for biology/sociality associations has repercussions on doing social research and on theory. This article argues that an in-depth discussion and critical reflection on the social configurations that are inscribed in, and reproduced by genomic data-intensive research is urgently needed. This is illustrated by debating a recent case: a large-scale genome-wide association study (GWAS) on sexual orientation that suggested partial genetic basis for same-sex sexual behaviour (Ganna et al. 2019b). This case is analysed from three angles: (1) the demonstration of how, in the process of genomics research, societal relations, understandings and categorizations are used and inscribed into social phenomena and outcomes; (2) the exploration of the ways that the (big) data-driven research is constituted by increasingly moving away from theory and methodological generation of theoretical concepts that foster the understanding of societal contexts and relations (Kitchin 2014a). Big Data Soc and (3) the demonstration of how the assumption of ‘free from theory’ in this case does not mean free of choices made, which are themselves restricted by data that are available. In questioning how key sociological categories are incorporated in a wider scientific debate on genetic conditions and knowledge production, the article shows how underlying classification and categorizations, which are inherently social in their production, can have wide ranging implications. The conclusion cautions against the marginalization of social science in the wake of developments in data-driven research that neglect social theory, established methodology and the contextual relevance of the social environment

Big data · Biology · Data science · Epistemology · Social research · Social science · Sociality · Sociology · Computer Science · Contemporary Sociological Theory and Practice · Genetic Associations and Epidemiology · Psychology · Race, Genetics, and Society · Ecology

  • Ethical, legal, and social implications in research biobanking

    Open Access•Olga Tzortzatou-Nanopoulou, Kaya Akyüz et al.•Developing World Bioethics•2024

  • High and Tight, Please

    Open Access•Robert W Mitchell•Sexuality & Culture•2021

  • Towards digital society management and ‘capitalism 4.0’ in contemporary Russia

    Open Access•Elena G Popkova, Aleksei V Bogoviz et al.•Humanities and Social Sciences…•2021

  • Rebuilding Geography for the 21st century through disciplinary reunification and social engagement

    Open Access•Weidong Liu, Han Cheng et al.•Environment and Planning F•2022

  • Post-identifiability in changing sociotechnological genomic data environments

    Open Access•Kaya Akyüz, Melanie Goisauf et al.•BioSocieties•2024

  • Biobanking and risk assessment

    Open Access•Kaya Akyüz, Gauthier Chassang et al.•Life Sciences Society and Policy•2021

  • Gender

    Suzanne J Kessler, Wendy Mckenna•Gender•1985

  • Paradoxes of gender

    Judith Lorber•Paradoxes of gender•1994

  • The Data Revolution

    Rob Kitchin•The Data Revolution•2014

  • The Postgenomic Condition

    Jenny Reardon•The Postgenomic Condition•2017

  • The DNA Mystique

    Dorothy Nelkin, M Susan Lindee et al.•The DNA Mystique•2004

  • Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior

    Open Access•Andrea Ganna, Karin J H Verweij et al.•Science•2019

  • A Linkage Between DNA Markers on the X Chromosome and Male Sexual Orientation

    Open Access•Dean H Hamer, Stella Hu et al.•Science•1993

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Open Access•Aysu Okbay, Jonathan P Beauchamp et al.•Nature•2016

  • Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

    Open Access•23andMe Research Team, James J Lee et al.•Nature Genetics•2018

  • Studies in ethnomethodology

    Harold Garfinkel•Studies in ethnomethodology•1984

  • Distinction

    Pierre Bourdieu, Tony Bennett-undifferentiated•Distinction•1984

  • Queer Genes

    Open Access•D A Griffiths•Journal of Critical Realism•2016

  • Distinction

    Pierre Bourdieu•Food and Culture•2018

  • Sorting Things Out

    G C Bowker, Susan Leigh Star•Sorting Things Out•1999

  • States of Knowledge

    Sheila Jasanoff•States of Knowledge•2004

  • Gender Trouble

    Judith Butler•Gender Trouble•2011

  • The Order of Things

    Michel Foucault•The order of things•2005

  • Genome editing

    Open Access•Paul Martins, Michael Morrison et al.•New Genetics and Society•2020

  • Shifting metaphors in direct-to-consumer genetic testing

    Open Access•Paula Saukko•New Genetics and Society•2017

  • Is personalized medicine different? (Reinscription

    Open Access•Barbara Prainsack•British Journal of Sociology•2015

  • Does Knowing Why Someone is Gay Influence Tolerance? Genetic, Environmental, Choice, and “Reparative” Explanations

    Open Access•Robert W Mitchell, Lana Dezarn•Sexuality & Culture•2014

  • The Social Construction of Gender

    Open Access•Janis S Bohan•Psychology of Women Quarterly•1992

  • Biased Assimilation and Attitude Polarization in Response to Learning About Biological Explanations of Homosexuality

    Open Access•Guy A Boysen, David L Vogel•Sex Roles•2007

  • The Life of the Gay Gene

    Kate O’riordan, Kate O'Riordan•The Journal of Sex Research•2012

  • Frameworks of desire

    Open Access•A Fausto-Sterling, Anne Fausto‐sterling•Daedalus•2007

  • The Promise and Challenges of Incorporating Genetic Data into Longitudinal Social Science Surveys and Research

    D Conley•Biodemography and Social Biology•2009

  • Big Data, new epistemologies and paradigm shifts

    Open Access•Rob Kitchin•Big Data & Society•2014

  • What difference does quantity make? On the epistemology of Big Data in biology

    Open Access•Sabina Leonelli, Leonelli•Big Data & Society•2014

  • Genetic correlates of social stratification in Great Britain

    Open Access•Abdel Abdellaoui, David Hugh-Jones et al.•Nature Human Behaviour•2019

  • Genetic essentialism

    Ilan Dar-Nimrod, Steven J Heine•Psychological Bulletin•2011

  • The Social as Signal in the Body of Chromatin

    Open Access•H Landecker•The Sociological Review•2016

  • The Birth of the Clinic

    Michel Foucault•Birth of the Clinic•2012

  • Situated Knowledges

    Donna Haraway•Feminist Studies•1988

  • Constructing the 'Gay Gene' in the News

    Open Access•Peter Conrad, Susan Marken•Health An Interdisciplinary…•2001

  • Biology without Biologism

    Open Access•Massimo Meloni, Maurizio Meloni•Sociology•2014

  • The Coming Crisis of Empirical Sociology

    Open Access•M Savage, Roger Burrows•Sociology•2007

  • From Social Structure to Gene Regulation, and Back

    H Landecker, Aaron Panofsky•Annual Review of Sociology•2013

  • The Datafication of Health

    Open Access•M Ruckenstein, Natasha Dow Schüll•Annual Review of Anthropology•2017

  • A mirage of genes

    Open Access•Peter Conrad•Sociology of Health & Illness•1999

  • Sequencing and Its Consequences

    Sara Shostak, Peter Conrad et al.•American Journal of Sociology•2008

  • Genetic risk and the birth of the somatic individual

    Carlos Novas, Nikolas Rose•Economy and Society•2000

Citations per year1.2
Citation span2021 - 2024 (4)
Highly citedNo

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