Phylogeography of mitochondrial DNA in western Europe

Dados Bibliográficos

ID23328161
AutoresMartin B Richards (0000-0003-3118-0967, John Radcliffe Hospital, autor correspondente), Vincent Macaulay (0000-0001-9084-2700, John Radcliffe Hospital), V A MACAULAY, H-J BANDELT, Bryan Sykes (John Radcliffe Hospital), B C SYKES
Ano1998
Volume62
Fascículo3
Páginas241-260
Data de publicação1998-05-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoAnnals of Human Genetics (JOURNAL)
Identificadores do periódicoISSN: 0003-4800 • E-ISSN: 1469-1809
EditoraWiley (PUBLISHER • GB)
DOI10.1046/j.1469-1809.1998.6230241.x
PMID9803269
OpenAlexW1974472861
IdiomaEN
Citações recebidas97
Referências citadas10

For most of the past century, prehistorians have had to rely on the fossil and archaeological records in order to reconstruct the past. In the last few decades, this evidence has been substantially supplemented from classical human genetics. More recently, phylogenetic analyses of DNA sequences that incorporate geographical information have provided a high‐resolution tool for the investigation of prehistoric demographic events, such as founder effects and population expansions. These events can be dated using a molecular clock when the mutation rate and founder haplotypes are known. We have previously applied such methods to sequence data from the mitochondrial DNA control region, to suggest that most extant mitochondrial sequences in western Europe have a local ancestry in the Early Upper Palaeolithic, with a smaller proportion arriving from the Near East in the Neolithic. Here, we describe a cladistic notation for mitochondrial variation and expand upon our earlier analysis to present a more detailed portrait of the European mitochondrial record.

Ancient DNA · Biology · Evolutionary biology · Gene · Genealogy · Genotype · Geography · Haplogroup · Haplotype · Mitochondrial DNA · Molecular clock · mtDNA control region · Phylogenetic tree · Phylogeography · Population · Prehistory · Sequence (biology) · Demography · Forensic and Genetic Research · Genetic diversity and population structure · Genetics · Genomics and Phylogenetic Studies · History · Paleontology