Depression and cardiovascular disease

A clinical review

Datos Bibliográficos

ID23360951
AutoresDavid L Hare (0000-0001-9554-6556, The University of Melbourne, autor de correspondencia), Samia R Toukhsati (0000-0002-2937-0895, Austin Health), Peter Johansson (0000-0002-0046-5348, Linköping University), Tiny Jaarsma (0000-0002-4197-4026, Linköping University)
Año2014
Volumen35
Número21
Páginas1365-1372
Fecha de publicación2014-06-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaEuropean Heart Journal (JOURNAL)
Identificadores de la revistaISSN: 0195-668X • E-ISSN: 1522-9645
EditorialOxford University Press (OUP) (PUBLISHER)
DOI10.1093/eurheartj/eht462
PMID24282187
OpenAlexW2127484731
IdiomaEN
Citas recibidas79
Referencias citadas100

Cardiovascular disease (CVD) and depression are common. Patients with CVD have more depression than the general population. Persons with depression are more likely to eventually develop CVD and also have a higher mortality rate than the general population. Patients with CVD, who are also depressed, have a worse outcome than those patients who are not depressed. There is a graded relationship: the more severe the depression, the higher the subsequent risk of mortality and other cardiovascular events. It is possible that depression is only a marker for more severe CVD which so far cannot be detected using our currently available investigations. However, given the increased prevalence of depression in patients with CVD, a causal relationship with either CVD causing more depression or depression causing more CVD and a worse prognosis for CVD is probable. There are many possible pathogenetic mechanisms that have been described, which are plausible and that might well be important. However, whether or not there is a causal relationship, depression is the main driver of quality of life and requires prevention, detection, and management in its own right. Depression after an acute cardiac event is commonly an adjustment disorder than can improve spontaneously with comprehensive cardiac management. Additional management strategies for depressed cardiac patients include cardiac rehabilitation and exercise programmes, general support, cognitive behavioural therapy, antidepressant medication, combined approaches, and probably disease management programmes.

Alternative medicine · Antidepressant · Anxiety · Depression (economics) · Disease · Intensive care medicine · Management of depression · Pathology · Population · Psychiatry · Quality of life (healthcare) · Cardiac Health and Mental Health · Heart Rate Variability and Autonomic Control · Internal Medicine · Medicine · Mental Health Treatment and Access