Skip to main content

ETHNOS_APP

Home • Search • Journals • List 0

Geographical Detectors‐Based Health Risk Assessment and its Application in the Neural Tube Defects Study of the Heshun Region, China

Bibliographic Data

ID23376166
AuthorsJinfeng Wang (0000-0002-6687-9420, Chinese Academy of Sciences, corresponding author), Jin‐Feng Wang, Xin‐Hu Li (Chinese Academy of Sciences), George Christakos (0000-0002-1865-5764, San Diego State University), Yi‐Lan Liao (Chinese Academy of Sciences), Tin Zhang, Zhang Tin (Beijing Institute of Neurosurgery), Xue Gu (0009-0000-1243-308X, Beijing Institute of Neurosurgery), Xiaoying Zheng (0000-0003-1966-044X, Peking University), Xiao‐Ying Zheng
Year2010
Volume24
Issue1
Pages107-127
Publication date2010-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueInternational Journal of Geographical Information Systems (JOURNAL)
Journal identifiersISSN: 0269-3798 • E-ISSN: 1362-3087
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/13658810802443457
OpenAlexW2163283323
LanguageEN
Citations received356
References cited41

Physical environment, man‐made pollution, nutrition and their mutual interactions can be major causes of human diseases. These disease determinants have distinct spatial distributions across geographical units, so that their adequate study involves the investigation of the associated geographical strata. We propose four geographical detectors based on spatial variation analysis of the geographical strata to assess the environmental risks of health: the risk detector indicates where the risk areas are; the factor detector identifies factors that are responsible for the risk; the ecological detector discloses relative importance between the factors; and the interaction detector reveals whether the risk factors interact or lead to disease independently. In a real‐world study, the primary physical environment (watershed, lithozone and soil) was found to strongly control the neural tube defects (NTD) occurrences in the Heshun region (China). Basic nutrition (food) was found to be more important than man‐made pollution (chemical fertilizer) in the control of the spatial NTD pattern. Ancient materials released from geological faults and subsequently spread along slopes dramatically increase the NTD risk. These findings constitute valuable input to disease intervention strategies in the region of interest.

Biology · Cartography · China · Detector · Environmental health · Geography · Health risk assessment · Human health · Risk analysis (engineering) · Risk assessment · Watershed · Computer Science · Ecology · Environmental and Social Impact Assessments · Environmental Science · Medicine · Pollution · Spatial and Panel Data Analysis

  • Decomposition of anthropogenic and climate forces of carbon sequestration in the urban agglomeration

    Open Access•Keyu Luo, Zhenyu Wang et al.•Cities•2026

  • Digital Trade Feature Map

    Open Access•Sijing Ye, Changqing Song et al.•ISPRS International Journal of…•2020

  • Spatio-Temporal Patterns of County Population Shrinkage and Influencing Factors in the North–South Transitional Zone of China

    Open Access•Tong Wu, Beibei Ma et al.•International Journal of…•2022

  • Assessment of Ecosystem Health and Its Key Determinants in the Middle Reaches of the Yangtze River Urban Agglomeration, China

    Open Access•Fengjian Ge, Guiling Tang et al.•International Journal of…•2022

  • Spatial Coupling Coordination Evaluation of Mixed Land Use and Urban Vitality in Major Cities in China

    Open Access•Lijing Dong, Lingyu Zhang•International Journal of…•2022

  • Ecological Risk Assessment and Protection Zone Identification for Linear Cultural Heritage

    Open Access•Li Li, Rundong Feng et al.•International Journal of…•2021

  • Spatio-Temporal Evolution and Influencing Factors of Ecological Well-Being Performance from the Perspective of Strong Sustainability

    Open Access•Zhicheng Lai, Li Lei et al.•International Journal of…•2023

  • Neglected Urban Villages in Current Vector Surveillance System

    Open Access•Sijia Wu, Hongyan Ren et al.•International Journal of…•2019

  • Spatial Differentiation of Digital Rural Development and Influencing Factors in the Yellow River Basin, China

    Open Access•Jiamin Ren, Chenrouyu Zheng et al.•International Journal of…•2022

  • Spatiotemporal Evolution and Driving Forces of Vegetation Cover in the Urumqi River Basin

    Open Access•Azimatjan Mamattursun, Han Yang et al.•International Journal of…•2022

  • Measuring Spatial Patterns of Health Care Facilities and Their Relationships with Hypertension Inpatients in a Network-Constrained Urban System

    Open Access•Zhensheng Wang, Ke Nie•International Journal of…•2019

  • Spatiotemporal Evolution of Non-Grain Production of Cultivated Land and Its Underlying Factors in China

    Open Access•Zhiyuan Zhu, Zhenzhong Dai et al.•International Journal of…•2022

  • Assessing local determinants of neural tube defects in the Heshun Region, Shanxi Province, China

    Open Access•Jinfeng Wang, Jin-Feng Wang et al.•BMC Public Health•2010

  • Spatio-temporal variation in tuberculosis incidence and risk factors for the disease in a region of unbalanced socio-economic development

    Open Access•Li Wang, Chengdong Xu et al.•BMC Public Health•2021

  • Integration of a Kalman filter in the geographically weighted regression for modeling the transmission of hand, foot and mouth disease

    Open Access•Bisong Hu, Wen-qing Qiu et al.•BMC Public Health•2020

  • Spatiotemporal matching between medical resources and population ageing in China from 2008 to 2017

    Open Access•Junming Li, Xinglin Chen et al.•BMC Public Health•2020

  • A spatial model to predict the incidence of neural tube defects

    Open Access•Lianfa Li, Jinfeng Wang et al.•BMC Public Health•2012

  • Spatial Sampling

    Open Access•Jinfeng Wang, Jin‐Feng Wang•International Encyclopedia of…•2018

  • An optimal parameters-based geographical detector model enhances geographic characteristics of explanatory variables for spatial heterogeneity analysis

    Open Access•Yongze Song, Jinfeng Wang et al.•GIScience & Remote Sensing•2020

  • A measure of spatial stratified heterogeneity

    Open Access•Jinfeng Wang, Jin-Feng Wang et al.•Ecological Indicators•2016

  • Spatiotemporal differentiation and the factors influencing urbanization and ecological environment synergistic effects within the Beijing-Tianjin-Hebei urban agglomeration

    Open Access•Zhenbo Wang, Longwu Liang et al.•Journal of Environmental Management•2019

  • Understanding the modifiable areal unit problem in dockless bike sharing usage and exploring the interactive effects of built environment factors

    Feng Gao, Shaoying Li et al.•International Journal of…•2021

  • Environmental health risk detection with GeogDetector

    Open Access•Jinfeng Wang, Jin-Feng Wang et al.•Environmental Modelling & Software•2012

  • Urbanization altered atmospheric humidity diurnally and seasonally through ecohydrological processes in five urban agglomerations in China

    Open Access•Xiaolin Huang, Kailun Jin et al.•Environmental Research Letters•2022

  • Effect of permafrost degradation on grassland net primary productivity in Qinghai–Tibet Plateau

    Open Access•Jianan Hu, Zhuotong Nan et al.•Environmental Research Letters•2024

  • Permafrost sensitivity to global warming of 1.5 °C and 2 °C in the Northern Hemisphere

    Open Access•Lei Liu, Dongsheng Zhao et al.•Environmental Research Letters•2020

  • Community forestry dominates the recent land greening amid climate change in Nepal

    Open Access•Shenshen Gao, Lang Wang et al.•Environmental Research Letters•2023

  • Observed evolution of global climate change hotspots

    Open Access•Zhuoya Du, Zongliang Du et al.•Environmental Research Letters•2025

  • The scenario-based variations and causes of future surface soil moisture across China in the twenty-first century

    Open Access•Keke Fan, Qiang Zhang et al.•Environmental Research Letters•2021

  • Spatial Distribution Characteristics of the Rural Tourism Villages in the Qinghai-Tibetan Plateau and Its Influencing Factors

    Open Access•Jianwei Qi, Yayan Lu et al.•International Journal of…•2022

  • Spatiotemporal Interaction and Socioeconomic Determinants of Rural Energy Poverty in China

    Open Access•Siyou Xia, Yu Yang et al.•International Journal of…•2022

  • Spatial analysis of the impact of urban built environment on cardiovascular diseases

    Open Access•Shuguang Deng, Jinlong Liang et al.•BMC Public Health•2024

  • Spatiotemporal Variation of Soil Erosion Characteristics in the Qinghai Lake Basin Based on the InVest Model

    Open Access•Zhen Chen, Xiaohong Gao et al.•International Journal of…•2023

  • Individual and Interactive Effects of Socio-Ecological Factors on Dengue Fever at Fine Spatial Scale

    Open Access•Zheng Cao, Tao Liu et al.•International Journal of…•2017

  • Ten years of China’s new healthcare reform

    Open Access•Jiang Chen, Chen Jiang et al.•BMC Public Health•2021

  • Construction of a Territorial Space Classification System Based on Spatiotemporal Heterogeneity of Land Use and Its Superior Territorial Space Functions and Their Dynamic Coupling

    Open Access•Dinghua Ou, Qi Zhang et al.•International Journal of…•2021

  • The Pattern and Local Push Factors of Rural Depopulation in Less-Developed Areas

    Open Access•Zhonglei Yu, Hua Zhang et al.•International Journal of…•2022

  • Quantifying the Spatiotemporal Heterogeneity of PM2.5 Pollution and Its Determinants in 273 Cities in China

    Open Access•Li Yang, Chunyan Qin et al.•International Journal of…•2023

  • Influence of Tourism Economy on Air Quality—An Empirical Analysis Based on Panel Data of 102 Cities in China

    Open Access•Fen Zhang, Haochen Peng et al.•International Journal of…•2022

  • Spatial Analysis of Built Environment Risk for Respiratory Health and Its Implication for Urban Planning

    Open Access•Lan Wang, Wenyao Sun et al.•International Journal of…•2019

  • Exploring Spatial Influence of Remotely Sensed PM2.5 Concentration Using a Developed Deep Convolutional Neural Network Model

    Open Access•Junming Li, Meijun Jin et al.•International Journal of…•2019

  • Alike but also different

    Open Access•Lei Jiang, Luhong Jiang et al.•BMC Public Health•2023

  • Modelling and prediction of global non-communicable diseases

    Open Access•Yang Wang, Jinfeng Wang•BMC Public Health•2020

  • Integrating Spatial Heterogeneity into an Analysis between Ecosystem Service Value and Its Driving Factors

    Open Access•Yuqing Zhao, Zenglin Han et al.•International Journal of…•2022

  • Mining Eco-Efficiency Measurement and Driving Factors Identification Based on Meta-US-SBM in Guangxi Province, China

    Open Access•Yonglin Li, Zhili Zuo et al.•International Journal of…•2021

  • Quantitative Analysis of a Spatial Distribution and Driving Factors of the Urban Heat Island Effect

    Open Access•Meizi You, Riwen Lai et al.•International Journal of…•2021

  • Spatial-temporal heterogeneity of hand, foot and mouth disease and impact of meteorological factors in arid/ semi-arid regions

    Open Access•Jie Li, Xiangxue Zhang et al.•BMC Public Health•2019

  • Spatiotemporal Distribution of Hand, Foot, and Mouth Disease in Guangdong Province, China and Potential Predictors, 2009–2012

    Open Access•Yijing Wang, Ying‐Si Lai et al.•International Journal of…•2019

  • Spatial Pattern Evolution and Influencing Factors on Agricultural Non-Point Source Pollution in Small Town Areas under the Background of Rapid Industrialization

    Open Access•Mingtao Yan, Jianji Zhao et al.•International Journal of…•2023

  • Spatial-temporal detection of risk factors for bacillary dysentery in Beijing, Tianjin and Hebei, China

    Open Access•Chengdong Xu, Yuanyuan Li et al.•BMC Public Health•2017

  • Spatiotemporal Analysis of Gastrointestinal Tumor (GI) with Kernel Density Estimation (KDE) Based on Heterogeneous Background

    Open Access•Zhenjie Yang, Sanwei He et al.•International Journal of…•2022

  • Geographical Clustering and Environmental Determinants of Schistosomiasis from 2007 to 2012 in Jianghan Plain, China

    Open Access•Yingnan Niu, Rendong Li et al.•International Journal of…•2018

  • Socioeconomic Drivers of PM2.5 in the Accumulation Phase of Air Pollution Episodes in the Yangtze River Delta of China

    Open Access•Lou Cai-rong, Cai-Rong Lou et al.•International Journal of…•2016

  • Spatial and Temporal Evolution of Land Use and the Response of Habitat Quality in Wusu, China

    Open Access•Yiming Wei, Hongwei Wang et al.•International Journal of…•2022

  • Spatiotemporal Variations in Gastric Cancer Mortality and Their Relations to Influencing Factors in S County, China

    Open Access•Cheng Cui, Baohua Wang et al.•International Journal of…•2019

  • Spatiotemporal Variations and Driving Factors of Air Pollution in China

    Open Access•Dongsheng Zhan, Mei-Po Kwan et al.•International Journal of…•2017

  • The Nonlinear Impact of Mobile Human Activities on Vegetation Change in the Guangdong–Hong Kong–Macao Greater Bay Area

    Open Access•Qionghuan Liu, Renzhong Guo et al.•International Journal of…•2023

  • Spatiotemporal trajectory of life expectancy and its disparity in China 2000–2030

    Open Access•Yuqing Feng, Jinfeng Wang et al.•BMC Public Health•2025

  • Evaluation Methods for Water Resource Suitability in Territorial Spatial Planning

    Open Access•Jiuyi Li•International Journal of…•2022

  • Spatial Characteristics of Heavy Metals in Street Dust of Coal Railway Transportation Hubs

    Open Access•Dongyue Li, Yilan Liao•International Journal of…•2018

  • Spatial Differentiation and Tradeoff–Synergy of Rural Multifunction at the County Scale in Anhui Province in the China’s Traditional Agricultural Areas

    Open Access•Rongtian Zhang•International Journal of…•2022

  • Spatial and Temporal Characteristics of Hand-Foot-and-Mouth Disease and Their Influencing Factors in Urumqi, China

    Open Access•Yibo Gao, Hongwei Wang et al.•International Journal of…•2021

  • Evaluation of the Protection Effectiveness of Natural Protected Areas on the Qinghai–Tibet Plateau Based on Ecosystem Services

    Open Access•Mengdi Fu, Jun Wang et al.•International Journal of…•2023

  • Identification of Health Risks of Hand, Foot and Mouth Disease in China Using the Geographical Detector Technique

    Open Access•Jixia Huang, Jinfeng Wang et al.•International Journal of…•2014

  • Analysis of the Spatial Relationship between Ecosystem Regulation Services and Rural Tourism

    Open Access•Junying Wang, Guifeng Han et al.•International Journal of…•2023

  • Spatial pattern of the population casualty rate caused by super typhoon Lekima and quantification of the interactive effects of potential impact factors

    Open Access•Xiangxue Zhang, Juan Nie et al.•BMC Public Health•2021

  • Spatial Characteristics of Life Expectancy and Geographical Detection of Its Influencing Factors in China

    Open Access•Yafei Wu, Ke Hu et al.•International Journal of…•2020

  • Coupling Coordination and Influencing Factors among Tourism Carbon Emission, Tourism Economic and Tourism Innovation

    Open Access•Yue Pan, Gangmin Weng et al.•International Journal of…•2021

  • Analysis of Heavy Metal Sources in the Soil of Riverbanks Across an Urbanization Gradient

    Open Access•Shudi Zuo, Shaoqing Dai et al.•International Journal of…•2018

  • Geographical Detector-Based Spatial Modeling of the Covid-19 Mortality Rate in the Continental United States

    Open Access•Han Yue, Tao Hu•International Journal of…•2021

  • Spatiotemporal Distribution Characteristics and Driving Forces of PM2.5 in Three Urban Agglomerations of the Yangtze River Economic Belt

    Open Access•Jin-Wei Yan, Fei Tao et al.•International Journal of…•2021

  • Spatial association between outdoor air pollution and lung cancer incidence in China

    Open Access•Dingfan Xing, D F Xing et al.•BMC Public Health•2019

  • Spatiotemporal Evolution and Drivers of Total Health Expenditure across Mainland China in Recent Years

    Open Access•Junming Li, Xiulan Han•International Journal of…•2022

  • Spatiotemporal Pattern of Urban-Rural Integration Development and Its Driving Mechanism Analysis in Hangzhou Bay Urban Agglomeration

    Open Access•Caiyao Xu, Chen Qian et al.•International Journal of…•2022

  • Spatiotemporal evolution of global population ageing from 1960 to 2017

    Open Access•Junming Li, Xiulan Han et al.•BMC Public Health•2019

  • Spatio-Temporal Evolution and Influence Mechanism of Habitat Quality in Guilin City, China

    Open Access•Yunlin He, Yanhua Mo et al.•International Journal of…•2022

  • Analysis of Land Use Change Drivers and Simulation of Different Future Scenarios

    Open Access•Lintao Liu, Shouchao Yu et al.•International Journal of…•2023

  • Spatiotemporal Variability and Influencing Factors of Aerosol Optical Depth over the Pan Yangtze River Delta during the 2014–2017 Period

    Open Access•Liang Cheng, Long Li et al.•International Journal of…•2019

  • Spatio-Temporal Changes in Land Use and Habitat Quality of Hobq Desert along the Yellow River Section

    Open Access•Ruibing Meng, Jiale Cai et al.•International Journal of…•2023

  • Geographical Detection of Traffic Accidents Spatial Stratified Heterogeneity and Influence Factors

    Open Access•Yuhuan Zhang, Huapu Lu et al.•International Journal of…•2020

  • Speciation Variation and Bio-Activation of Soil Heavy Metals (Cd and Cr) in Rice-Rape Rotation Lands in Karst Regions

    Open Access•Jiachun Zhang, Guiting Mu et al.•International Journal of…•2021

  • Spatio-Temporal Variations of Satellite-Based PM2.5 Concentrations and Its Determinants in Xinjiang, Northwest of China

    Open Access•Wei Wang, Alim Samat et al.•International Journal of…•2020

  • Spatial Characteristics and Factor Analysis of Pollution Emission from Heavy-Duty Diesel Trucks in the Beijing–Tianjin–Hebei Region, China

    Open Access•Beibei Zhang, Sheng Wu et al.•International Journal of…•2019

  • Temporal and Spatial Variation and Driving Forces of Soil Erosion on the Loess Plateau before and after the Implementation of the Grain-for-Green Project

    Open Access•Jiaying He, Xiaohui Jiang et al.•International Journal of…•2022

  • Temporal and Spatial Heterogeneity of Soil Erosion and a Quantitative Analysis of its Determinants in the Three Gorges Reservoir Area, China

    Open Access•Lin Chu, Tiancheng Sun et al.•International Journal of…•2020

  • The Link between Landscape Characteristics and Soil Losses Rates over a Range of Spatiotemporal Scales

    Open Access•Qing Li, Yong Zhou et al.•International Journal of…•2021

  • Spatial–Temporal Characteristics of Illegal Land Use and Its Driving Factors in China from 2004 to 2017

    Open Access•Hongwei Zhang, Zhanqi Wang et al.•International Journal of…•2021

  • Temporal and Spatial Heterogeneity of PM2.5 Related to Meteorological and Socioeconomic Factors across China during 2000–2018

    Open Access•Xiangxue Zhang, Changxiu Cheng•International Journal of…•2022

  • Long-term effects of climate factors on dengue fever over a 40-year period

    Open Access•Chengdong Xu, Jingyi Xu et al.•BMC Public Health•2024

  • Identifying Driving Forces of Built-Up Land Expansion Based on the Geographical Detector

    Open Access•Yongwei Liu, Xiaoshu Cao et al.•International Journal of…•2020

  • Geographical evolutionary pathway of global tuberculosis incidence trends

    Open Access•Yanhui Lei, Jinfeng Wang et al.•BMC Public Health•2023

  • Spatial–Temporal Patterns of Population Aging in Rural China

    Open Access•Chan Chen, Jie Li et al.•International Journal of…•2022

  • Mapping the Spatial–Temporal Distribution and Migration Patterns of Men Who Have Sex with Men in Mainland China

    Open Access•Dacang Huang, Jinfeng Wang et al.•International Journal of…•2020

  • Determining the effects of social–environmental factors on the incidence and mortality of lung cancer in China based on remote sensing and GIS technology during 2007–2016

    Open Access•Bin Xie, Jingwen Wang et al.•BMC Public Health•2025

  • Spatial-Temporal Differentiation Analysis of Agricultural Land Use Intensity and Its Driving Factors at the County Scale

    Open Access•Li Yu, Zhanqi Wang et al.•International Journal of…•2020

  • Multiscale Characteristics and Drivers of the Bundles of Ecosystem Service Budgets in the Su-Xi-Chang Region, China

    Open Access•Yue Wang, Wen Zhu et al.•International Journal of…•2022

  • Spatio-Temporal Pattern and Risk Factor Analysis of Hand, Foot and Mouth Disease Associated with Under-Five Morbidity in the Beijing–Tianjin–Hebei Region of China

    Open Access•Chengdong Xu•International Journal of…•2017

  • Effects of Meteorological Factors and Air Pollutants on Covid-19 Transmission under the Action of Control Measures

    Open Access•Fei Han, Xinqi Zheng et al.•International Journal of…•2022

  • Spatiotemporal heterogeneity and long-term impact of meteorological, environmental, and socio-economic factors on scrub typhus in China from 2006 to 2018

    Open Access•Jiaojiao Qian, Yi-Fan Wu et al.•BMC Public Health•2024

  • Spatial analysis of overweight prevalence in China

    Open Access•Peihan Wang, Kexin Li et al.•BMC Public Health•2023

  • Human Frontiers, Environments and Disease

    Open Access•Tony McMichael•Human Frontiers, Environments and…•2001

  • Spatial Data Analysis

    Open Access•Robert Haining•Spatial Data Analysis•2003

  • A spatial scan statistic

    Martin Kulldorff•Communications in Statistics -…•1997

  • Prevention of Neural-Tube Defects with Folic Acid in China

    R J Berry, Zhu Li et al.•New England Journal of Medicine•1999

  • Exploratory spatial data analysis for the identification of risk factors to birth defects

    Open Access•Jilei Wu, Jinfeng Wang et al.•BMC Public Health•2004

  • Child malnutrition and school performance in China

    Open Access•D T Jamison•Journal of Development Economics•1986

  • Human Frontiers, Environments, and Disease

    Richard N Cooper, Tony McMichael•Foreign Affairs•2002

  • Local Indicators of Spatial Association—Lisa

    Open Access•Luc Anselin•Geographical Analysis•1995

  • A study of the breast cancer dynamics in North Carolina

    Open Access•George Christakos, Jaim-Jou Lai•Social Science & Medicine•1997

  • A novel method for studying population health impacts of spatiotemporal ozone distribution

    Open Access•George Christakos, Vikram M Vyas•Social Science & Medicine•1998

Unique citing works356
Citations per year22,25
Citation span2010 - 2026 (17)
Citation velocitycurrent
Highly citedYes
Citation typesNeutral: 343

Tools

Open DOISci-Hub
Ethnos_APP • Open Source Project • MIT License • Frontend v2.0.0 • Privacy and Cookies • API Documentation: api.ethnos.app/docs • API Source Code: GitHub • DOI: 10.5281/zenodo.17049435 • Frontend Source Code: GitHub • DOI: 10.5281/zenodo.17050053 • cruz.rio.br • Expectantes Misericordiae