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Evidence for DNA single-copy loci from prehistoric teeth. DNA protection depending on burial site

Bibliographic Data

ID3778996
AuthorsJoachim Burger (0000-0001-7630-9782, University of Göttingen), Hummel (0000-0002-3647-8968), Susanne Hummel, Bernd Herrmann (0009-0000-1851-8746)
Year1997
Volume55
Issue2
Pages193-198
Publication date1997-06-01
Open AccessNo
TypeARTICLE
VenueAnthropologischer Anzeiger (JOURNAL)
Journal identifiersISSN: 0003-5548 • E-ISSN: 2363-7099
PublisherS ch we iz er ba rt (PUBLISHER)
DOI10.1127/anthranz/55/1997/193
PMID9341086
OpenAlexW2434001332
LanguageEN
Citations received2

DNA-extracts from prehistoric roots of teeth were analyzed by PCR to investigate microsatellite-systems. At the same time the x/y-chromosome specific system Amel A/B was investigated. The samples were collected from different burial conditions of similar age. Factors leading to limited DNA-degradation are given. For the first time reproducible Quadruplex-amplification on single-copy loci of prehistoric tissue was obtained in samples from the Lichtenstein-Cave, Kr. Osterode/Harz. Positive results are explained by low temperature in the burial site. In addition the results show that desiccation allows DNA-preservation but cannot protect the DNA from damage due to microbial origin. Microorganisms can destroy DNA-structures completely.

Ancient DNA · Archaeology · Biology · Botany · Cave · Desiccation · DNA · Evolutionary biology · Gene · Geography · Microsatellite · Prehistory · Bacteriophages and microbial interactions · Ecology · Forensic and Genetic Research · Genetics · Medicine · Molecular Biology Techniques and Applications · Paleontology

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Citations per year0.09
Citation span2003 - 2011 (9)
Highly citedNo

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