Assessing Developmental Outcomes in Children from Kilifi, Kenya, Following Prophylaxis for Seizures in Cerebral Malaria
Bibliographic Data
| ID | 4227929 |
|---|---|
| Authors | A Abubakar (0000-0002-3686-7904, Centre for Geographic Medicine Research, Coast, Kemri, Kenya and Tilburg University, The Netherlands), Fons J R Van De Vijver (0000-0003-0220-2485, Tilburg University, The Netherlands and North-West University, South Africa), Sadik Mithwani (Kenya Medical Research Institute), Elizabeth Obiero (Kenya Medical Research Institute), Naomi Lewa (Kenya Medical Research Institute), Simon Kenga (Kenya Medical Research Institute), Khamis Katana (Kenya Medical Research Institute), Penny Holding (0000-0002-4159-9115, Centre for Geographic Medicine Research, Coast, Kemri, Kenya and University of Oxford, UK) |
| Year | 2007 |
| Volume | 12 |
| Issue | 3 |
| Pages | 417-430 |
| Publication date | 2007-05-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Health Psychology (JOURNAL) |
| Journal identifiers | ISSN: 1359-1053 • E-ISSN: 1461-7277 |
| Publisher | SAGE Publications Inc (PUBLISHER) |
| DOI | 10.1177/1359105307076230 |
| PMID | 17439993 |
| OpenAlex | W2096681863 |
| Language | EN |
| Citations received | 5 |
| References cited | 32 |
The purpose of the study was to develop a culture-informed measure of developmental outcome and to apply it to detect differences in developmental level between children with cerebral malaria enrolled in a clinical trial to control seizures during the acute phase of the illness. The instrument was administered to a sample of 180 children, three and 12 months after discharge from hospital. The measure demonstrated high internal consistency, good inter-observer reliability, age sensitivity and strong relations with parental report of child functioning. No association was found between performance, or change in performance, with the prophylactic regime administered. The results suggested that the use of Phenobarbital in controlling provoked seizures has no observable effect on cognitive function
Cerebral Malaria · Clinical trial · Cognition · Malaria · Phenobarbital · Plasmodium falciparum · Psychiatry · Epilepsy research and treatment · Malaria Research and Control · Medicine · Pharmacological Effects and Toxicity Studies · Immunology · Internal Medicine · Pediatrics
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| Unique citing works | 5 |
|---|---|
| Citations per year | 0,42 |
| Citation span | 2014 - 2018 (5) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 5 |