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Knee Ankyloses Associated with Tuberculosis from the Medieval Hungary - Differential Diagnosis Based on Medical Imaging Techniques

Knee Ankyloses Associated with Tuberculosis from the Medieval Hungary

Bibliographic Data

ID4682023
AuthorsLászló Paja (École Pratique des Hautes Études, corresponding author), Hélène Coqueugniot (0000-0002-1844-4588, Max Planck Institute for Evolutionary Anthropology), O Dutour (0000-0001-8134-788X, Laboratoire de Paléoanthropologie de l'EPHE; École Pratique des Hautes Études; Talence France), Renee Willmon (Western University), G L Farkas (Department of Biological Anthropology, Faculty of Science and Informatics; University of Szeged; Szeged Hungary), András Palkó (0000-0002-5370-6934, University of Szeged), György Pálfi (0000-0003-0989-4090, University of Szeged)
Year2015
Volume25
Issue3
Pages352-360
Publication date2015-05-01
Open AccessYes
TypeARTICLE
VenueInternational Journal of Osteoarchaeology (JOURNAL)
Journal identifiersISSN: 1047-482X • E-ISSN: 1099-1212
PublisherWiley (PUBLISHER • GB)
DOI10.1002/oa.2284
OpenAlexW1959858499
LanguageEN
Citations received3
References cited19

Osseous ankylosis of large joints that occurs secondary to infection is rarely described in developed countries, thanks to diagnostic techniques that allow early detection and treatment of the underlying infection. Evidence of the natural history and progression of the disease is now primarily studied through the observation and analysis of osteoarcheological specimens, and medical reports or books dating from the pre-antibiotic era. This report illustrates several cases where modern medical imaging techniques and ancient medical literature were successfully interpreted to diagnose rare, advanced-stage tuberculous alterations in osteoarcheological specimens. Two skeletons from the Bátmonostor cemetery (Hungary) demonstrate complete unilateral ankylosis of the knee. Macroscopic and radiographic examinations were undertaken to assess the extent of skeletal changes and determine their cause. Data obtained from computed tomography (CT) were constructed in 2D and 3D. The 2D CT images revealed cavities involving both the metaphyses and the epiphyses. The 3D reconstructions allowed us to reconstruct the more precise volumetric morphology of the circumscribed lytic lesions, as well as clear ‘image-mirror’ lacunar volumes. On the basis of the macroscopic and radiological analyses, extra-spinal tuberculous infection seems to have been the most probable etiology of these two cases. Copyright © 2012 John Wiley & Sons, Ltd

Ankylosis · Computed tomography · Differential diagnosis · Etiology · Medical imaging · Paleopathology · Pathology · Radiography · Radiology · Tuberculosis · Hematological disorders and diagnostics · Infectious Diseases and Tuberculosis · Medicine · Orthopedic Infections and Treatments · Orthodontics

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Citations per year0.75
Citation span2022 - 2025 (4)
Highly citedNo

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