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Comparative effects of ayahuasca and breathwork on self-reported cognitive flexibility, emotion regulation, positive affect, and sleep quality

Dados Bibliográficos

ID4711792
AutoresGiordano N Rossi (0000-0002-1952-1207, Universidade de São Paulo), Rishma S I Khubsing (Amsterdam University of Applied Sciences), Eline C H M Haijen (Maastricht University), Eline Haijen (0000-0002-1110-1486, Maastricht University), Natasha L Mason (0000-0001-7115-0389, Maastricht University), Martin Van Leerdam (Bare Statistics, 1841 GV Stompetoren, The Netherlands), Rafael G Dos Santos (0000-0003-2388-4745, Universidade de São Paulo), Jaime E C Hallak (0000-0002-8784-0189, Universidade de São Paulo), Kim P C Kuypers (0000-0001-7634-3809, Maastricht University)
Ano2025
Volume10
Fascículo1
Páginas75-87
Data de publicação2025-09-04
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoJournal of Psychedelic Studies (JOURNAL)
Identificadores do periódicoISSN: 2559-9283 • E-ISSN: 2559-9283
EditoraAkademiai Kiado Zrt (PUBLISHER)
DOI10.1556/2054.2025.00440
OpenAlexW4413975997
IdiomaEN
Referências citadas7

Background and aimsResearch on classical psychedelics like ayahuasca is increasingly focused on treating mental disorders and enhancing well-being. Ayahuasca has shown promise in improving cognitive flexibility, emotion regulation, and sleep, though findings are mixed and further research is needed. This study tracked participants over three months, assessing cognitive flexibility, positive affect, emotion regulation, and sleep before and after ayahuasca ceremonies, compared to a breathwork control group. The hypothesis was that ayahuasca would offer greater benefits than breathwork, with cognitive flexibility improvements preceding gains in emotion regulation and sleep.MethodsUsing a longitudinal observational study, we collected data from participants who attended either a single ayahuasca ceremony (involving two consecutive doses about 3 h apart) or a single breathwork session. Online questionnaires were administered via the Qualtrics platform one week before the interventions (baseline, T0) and at one, six, and twelve weeks (T1, T6, and T12) post-session.ResultsBoth treatments significantly improved cognitive flexibility, emotion regulation, positive affect, and sleep quality over time compared to baseline. Cognitive flexibility improvements preceded changes in emotion regulation, partially confirming our hypotheses.ConclusionsWhile this study showed lasting positive effects of ayahuasca and breathwork on cognitive flexibility, emotion regulation, positive affect, and sleep quality, the temporal order of these effects remains unclear. The role of attendee experience and internal motivation in these outcomes is also uncertain. Future research should include more frequent assessments closer to the experience and consider both the acute experience and participants' motivation to better understand the drivers of these changes

Affect (linguistics) · Ayahuasca · Biology · Cognition · Cognitive flexibility · Flexibility (engineering) · Sleep (system call) · Sleep quality · Clinical Psychology · Communication · Computer Science · Ecology · Neuroscience · Olfactory and Sensory Function Studies · Psychedelics and Drug Studies · Psychology · Sleep and Wakefulness Research

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