Prenatal Stress and Risk for Psychopathology
Specific Effects or Induction of General Susceptibility
Datos Bibliográficos
| ID | 4903323 |
|---|---|
| Autores | Anja C Huizink (0000-0003-2015-4819, University Medical Center Utrecht), Edu J H Mulder, E Mulder (0000-0002-5906-5867), Jan Buitelaar (0000-0001-8288-7757), Jan K Buitelaar |
| Año | 2004 |
| Volumen | 130 |
| Número | 1 |
| Páginas | 115-142 |
| Fecha de publicación | 2004-01-01 |
| Peer Reviewed | Sí |
| Open Access | No |
| Tipo | ARTICLE |
| Revista | Psychological Bulletin (JOURNAL) |
| Identificadores de la revista | ISSN: 0033-2909 • E-ISSN: 1939-1455 |
| Editorial | American Psychological Association (APA) (PUBLISHER) |
| DOI | 10.1037/0033-2909.130.1.115 |
| PMID | 14717652 |
| OpenAlex | W2164438435 |
| Idioma | EN |
| Citas recibidas | 31 |
| Referencias citadas | 233 |
This review focuses on prenatal stress as a risk factor for psychopathology. Evidence from animal studies is summarized, and the relevance of prenatal stress models in animals for human studies is discussed. In the offspring of prenatally stressed animals, overactivity and impaired negative feedback regulation of the hypothalamic-pituitary-adrenal axis are consistent findings and may reflect a pathophysiological mechanism involved in the development of psychopathology. Reduced activity of the opioid GABA/benzodiazepine, serotonin, and dopamine systems and increased activity of the sympathico-adrenal system have been found as well. These alterations have been linked to a diverse spectrum of psychopathology. Therefore, the evidence supports the view that exposure to prenatal stress may result in a general susceptibility to psychopathology, rather than exerting a direct effect on a specific form of psychopathology
Animal studies · Biology · Offspring · Pregnancy · Prenatal stress · Psychopathology · Anesthesia and Neurotoxicity Research · Birth, Development, and Health · Clinical Psychology · Endocrinology · Genetics · Internal Medicine · Medicine · Psychology · Stress Responses and Cortisol
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| Obras citantes distintas | 31 |
|---|---|
| Citas por año | 1,48 |
| Intervalo de citas | 2005 - 2024 (20) |
| Velocidad de citación | recent |
| Altamente citado | No |
| Tipos de cita | Neutras: 26 |