Adherence to antiretroviral therapy in children
A Study of Prevalence and Associated Factors
Bibliographic Data
| ID | 5176214 |
|---|---|
| Authors | Neiva Isabel Raffo Wachholz (Prefeitura Municipal de Porto Alegre), Jair Ferreira (0000-0002-8045-2941, Universidade Federal do Rio Grande do Sul) |
| Year | 2007 |
| Volume | 23 |
| Issue | suppl 3 |
| Pages | S424-S434 |
| Publication date | 2007-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Cadernos de Saude Publica (JOURNAL) |
| Journal identifiers | ISSN: 0102-311X • E-ISSN: 1678-4464 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/s0102-311x2007001500010 |
| PMID | 17992348 |
| OpenAlex | W2151061014 |
| SCIELO_PID | S0102-311X2007001500010 |
| Language | EN |
| Citations received | 6 |
| References cited | 14 |
The survival of children with AIDS has increased considerably with the use of more effective antiretrovirals, but the benefits of this therapy are limited by the difficulty of adherence to the treatment. This cross-sectional study aimed to estimate the prevalence of non-adherence to antiretrovirals among children residents in Porto Alegre, Rio Grande do Sul State, Brazil, and identifying associated factors. There were 194 child caregivers interviewed. The technique utilized to evaluate adherence allowed the detection of lack of understanding of the prescribed antiretroviral regimens, as well as conscious loss of doses. Non-adherence was defined when the child had taken less than 80% of the prescribed medication during the 24h period prior to the interview. A general prevalence of non-adherence was 49.5%, which was higher than that estimated. The non-institutional caregivers had a prevalence rate of 55.7%, while the institutional caregivers had 22.2%. In multivariate analysis, the education of the caregiver was found to have a borderline association with the outcome. Institutionalized children and those taken care of by people with a higher educational level appeared to have more protection against non-adherence to antiretroviral therapy
Antiretroviral therapy · Cross-sectional study · Family medicine · Human immunodeficiency virus (HIV) · Multivariate analysis · Viral load · Adolescent Sexual and Reproductive Health · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Internal Medicine · Medicine · Pediatrics
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| Unique citing works | 6 |
|---|---|
| Citations per year | 0.35 |
| Citation span | 2009 - 2015 (7) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 6 |