Monitoring adherence to antiretroviral treatment in Brazil
An Urgent Challenge
Bibliographic Data
| ID | 5224824 |
|---|---|
| Authors | Geisa Maria Rocha (0000-0001-8255-1559, Federal University of São João del-Rei), Gustavo Machado Rocha, Carla Jorge Machado (0000-0002-6871-0709, Universidade Federal de Minas Gerais), Francisco De Assis Acurcio (0000-0002-5880-5261, Universidade Federal de Minas Gerais), Mark Drew Crosland Guimarães (0000-0001-7932-3854, Universidade Federal de Minas Gerais) |
| Year | 2011 |
| Volume | 27 |
| Issue | suppl 1 |
| Pages | s67-s78 |
| Publication date | 2011-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Cadernos de Saude Publica (JOURNAL) |
| Journal identifiers | ISSN: 0102-311X • E-ISSN: 1678-4464 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/s0102-311x2011001300008 |
| PMID | 21503526 |
| OpenAlex | W2159380290 |
| SCIELO_PID | S0102-311X2011001300008 |
| Language | EN |
| Citations received | 9 |
| References cited | 27 |
The aim of this study was to describe the effect of non-adherence on the main laboratory outcomes, TCD4+ lymphocyte count and viral load, routinely used to monitor patients initiating treatment according to three different approaches to measure adherence to antiretroviral therapy. Among 288 participants, 22.9%, 31.9% and 74.3% were considered non-adherent, according to medical charts, self-report and pharmacy records, respectively. Depending on the adherence measures used, the average gain in TCD4+ lymphocyte count ranged from 142.4 to 195.4 cells/mm3 among adherent patients, and from 58.5 to 99.8 lymphocytes TCD4+/mm3 among those non-adherent. The average reduction on viral load ranged from 4.25 to 4.62 log copies/mL among the adherent patients, and from 1.99 to 4.07 log among those non-adherent. Monitoring antiretroviral adherence should be considered a priority in these public AIDS referral centers in order to identify patients at high risk of developing virologic failure. Early interventions are necessary in order to maintain the initial therapeutic regimens for longer periods
Antiretroviral therapy · Antiretroviral treatment · Family medicine · Human immunodeficiency virus (HIV) · Intensive care medicine · Medical record · Psychological intervention · Referral · Viral load · Emergency Medicine · HIV-related health complications and treatments · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Immunology · Internal Medicine · Medicine · Pharmacy
O remédio é o menor dos problemas
Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy
Individual and contextual factors of influence on adherence to antiretrovirals among people attending public clinics in Rio de Janeiro, Brazil
Perfil e adesão à terapia antirretroviral de pessoas vivendo com HIV/Aids
Measuring Adherence to Antiretroviral Treatment
Comparison of the predictive performance of adherence measures for virologic failure detection in people living with HIV
Aspectos relacionados à utilização de antirretrovirais em pacientes de alta complexidade no estado do Rio de Janeiro, Brasil
Fatores associados à adesão à Terapia Antirretroviral em adultos
Utilização de registros de dispensação de medicamentos na mensuração da adesão
Practical and Conceptual Challenges in Measuring Antiretroviral Adherence
Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection
The unequal variance t-test is an underused alternative to Student's t-test and the Mann–Whitney U test
Self-Report Measures of Antiretroviral Therapy Adherence
Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection
A computer-based assessment detects regimen misunderstandings and nonadherence for patients on HIV antiretroviral therapy
Desenvolvimento e validação de questionário multidimensional para medir não-adesão ao tratamento com medicamentos
Interrupção do acompanhamento clínico ambulatorial de pacientes infectados pelo HIV
The first ten years
Utilização dos registros de dispensação da farmácia como indicador da não-adesão à terapia anti-retroviral em indivíduos infectados pelo HIV
Adherence to antiretroviral therapy in children
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil
Início da terapia anti-retroviral em estágio avançado de imunodeficiência entre indivíduos portadores de HIV/Aids em Belo Horizonte, Minas Gerais, Brasil
| Unique citing works | 9 |
|---|---|
| Citations per year | 0,64 |
| Citation span | 2012 - 2021 (10) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 7 |